CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021919
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GDSL esterase/lipase LTL1 
Protein Synonyms/Alias
 Extracellular lipase LTL1; Lithium-tolerant lipase 1; AtLTL1; Li-tolerant lipase 1 
Gene Name
 LTL1 
Gene Synonyms/Alias
 At3g04290; T6K12.9 
Created Date
 July 27, 2013 
Organism
 Arabidopsis thaliana (Mouse-ear cress) 
NCBI Taxa ID
 3702 
Lysine Modification
Position
Peptide
Type
References
205EYGKILRKLYELGARacetylation[1]
Reference
 [1] Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis.
 Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ.
 Plant Physiol. 2011 Apr;155(4):1779-90. [PMID: 21311031] 
Functional Description
 Involved in the mechanisms of salt tolerance. Mediates resistance to LiCl and NaCl. 
Sequence Annotation
 ACT_SITE 36 36 Nucleophile (By similarity).
 ACT_SITE 326 326 By similarity.
 ACT_SITE 329 329 By similarity.
 CARBOHYD 117 117 N-linked (GlcNAc...) (Potential).
 CARBOHYD 354 354 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism; Reference proteome; Secreted; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 366 AA 
Protein Sequence
MNINCSPLGF LISLFFIVTF LAPQVKSRAF FVFGDSLVDN GNNDYLVTTA RADNYPYGID 60
YPTRRPTGRF SNGLNIPDII SEAIGMPSTL PYLSPHLTGE NLLVGANFAS AGIGILNDTG 120
IQFVNIIRIS KQMEYFEQYQ LRVSALIGPE ATQQLVNQAL VLITLGGNDF VNNYYLIPFS 180
ARSRQYALPD YVVYLISEYG KILRKLYELG ARRVLVTGTG AMGCAPAELA QHSRNGECYG 240
ALQTAAALFN PQLVDLIASV NAEIGQDVFV AANAYQMNMD YLSNPEQFGF VTSKVACCGQ 300
GPYNGIGLCT PVSNLCPNRD LYAFWDAFHP TEKANRIIVN QILTGSSKYM HPMNLSTAML 360
LDSSKI 366 
Gene Ontology
 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
 GO:0042538; P:hyperosmotic salinity response; IMP:UniProtKB.
 GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
 GO:0010226; P:response to lithium ion; IMP:UniProtKB.
 GO:0009751; P:response to salicylic acid stimulus; IDA:UniProtKB. 
Interpro
 IPR001087; Lipase_GDSL.
 IPR013831; SGNH_hydro-type_esterase_dom. 
Pfam
 PF00657; Lipase_GDSL 
SMART
  
PROSITE
 PS01098; LIPASE_GDSL_SER 
PRINTS