CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016994
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 547 
Protein Synonyms/Alias
  
Gene Name
 ZNF547 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
224CGKAFLCKSHLVRHQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 11 82 KRAB.
 ZN_FING 87 109 C2H2-type 1.
 ZN_FING 156 178 C2H2-type 2.
 ZN_FING 184 206 C2H2-type 3.
 ZN_FING 212 234 C2H2-type 4.
 ZN_FING 240 262 C2H2-type 5.
 ZN_FING 268 290 C2H2-type 6.
 ZN_FING 296 318 C2H2-type 7.
 ZN_FING 324 346 C2H2-type 8.
 ZN_FING 352 374 C2H2-type 9.
 ZN_FING 378 400 C2H2-type 10.  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 402 AA 
Protein Sequence
MAEMNPAQGH VVFEDVAIYF SQEEWGHLDE AQRLLYRDVM LENLALLSSL GCCHGAEDEE 60
APLEPGVSVG VSQVMAPKPC LSTQNTQPCE TCSSLLKDIL RLAEHDGTHP EQGLYTCPAH 120
LHQHQKEQIR EKLSRGDGGR PTFVKNHRVH MAGKTFLCSE CGKAFSHKHK LSDHQKIHTG 180
ERTYKCSKCG ILFMERSTLN RHQRTHTGER PYECNECGKA FLCKSHLVRH QTIHSGERPY 240
ECSECGKLFM WSSTLITHQR VHTGKRPYGC SECGKFFKCN SNLFRHYRIH TGKRSYGCSE 300
CGKFFMERST LSRHQRVHTG ERPYECNECG KFFSLKSVLI QHQRVHTGER PYECSECGKA 360
FLTKSHLICH QTVHTAAKQC SECGKFFRYN STLLRHQKVH TG 402 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB
 PF00096; zf-C2H2 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS