| Tag | Content |
|---|
| CPLM ID | CPLM-019889 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | von Willebrand factor A domain-containing protein 5A |
Protein Synonyms/Alias | Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog |
Gene Name | Vwa5a |
Gene Synonyms/Alias | Loh11cr2a |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 310 | QLRIEAAKETLLLLL | ubiquitination | [1] | | 538 | VTFSLQPKANDNFTI | ubiquitination | [1] | | 551 | TIHRLAAKSLIQTKD | ubiquitination | [1] | | 557 | AKSLIQTKDFGSQEA | ubiquitination | [1] | | 630 | SSFSGGFKGPQPRSL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in may contribute directly to or modify tumorigenesis (By similarity). |
Sequence Annotation | DOMAIN 1 131 VIT.
DOMAIN 281 469 VWFA.
MOD_RES 622 622 Phosphotyrosine. |
Keyword | Complete proteome; Phosphoprotein; Reference proteome; Tumor suppressor. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 793 AA |
Protein Sequence | MEHHCGLITS NKETVPLKNI SVTLSINEFV AAVVATLNYE NEEKVPLEAT FVFPMDEDSA 60
VYSFEALVDG KKIVAELQDK MKAHSEYEEA LSQGHQAYLL EEDDYSRDVF SCNVGNLQPG 120
AKVAVTLRYV QELPLETDGA LRYLLPAILN PRYQLSEQSA NSCLNIQKPT VPLEDLPYTL 180
NMTATITSQH GIERVQSNCS LSPIQYLTDD KTSAQVSLTE GHKFDRDVEL LIYYNEVHSP 240
SVAVEMGMLD MKPDSLMGAP SAMVSFYPDI PEVEASKACG EFVFLMDRSG SMDSPMSTEN 300
NSQLRIEAAK ETLLLLLKSL PMGCYFNIYG FGSSYEKFFP ESVKYTQDTM EDAVKRVKAL 360
KANLGGTEIL TPLCNIYKAS SIPGHPLQLF VFTDGEVSDT FSVIREVKLN SKKHRCFSFG 420
IGQGASTSLI KNIARVSGGT AVFITGKDRM QTKALGSLKF ALQCAVDNIS LSWDLPPGLS 480
VKMLSPEQLT IFRGQRLIIY AQLTGLMPQV ESTGAVCLKH ILQGRSLENR VTFSLQPKAN 540
DNFTIHRLAA KSLIQTKDFG SQEASKEEKE DVMNISLQSG VLSSFTAFIA INKELNKPVQ 600
GPLAHRVIPR PVMAGSSSMR FYSSFSGGFK GPQPRSLRVP AYDLCSAESA NLVLKKSACS 660
AIQKKKTNSS TNKSNLKKEH KAFGENAVVQ LISLQKANGS WELDEDLTKI LGTKSKDIKA 720
ANPAKHEDPS AWSTVLAVVW LHANGTDLKC EWELLERKAV AWLHDHAGSS IPMLVQAANS 780
LLKLSVNPAV FGV 793 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |