CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028209
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sc2 
Protein Synonyms/Alias
  
Gene Name
 Sc2 
Gene Synonyms/Alias
 CG10849; Dmel_CG10849 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
58ELKGKSLKDTDTLESacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Oxidoreductase; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 302 AA 
Protein Sequence
MELEILNAKN SKPYGKVKVP SGATPIGDLR ALIHKTLKQT PHANRQSLRL ELKGKSLKDT 60
DTLESLSLRS GDKIYVKDLG PQIGWKTVFL AEYAGPLIVY LIFYFRPELV YGKAASLPIS 120
LTTHIAAGCY TVHYVKRLLE TIFVHRFSHA TMPLRNLFKN CTYYWGFTAY VSYHVNHPQF 180
TSPCMCTVWG ALGAFALCEL GNFSVHIALR NLRPPGTKVR KIPVADGNPL TKLFDLVSCP 240
NYTYEIGAWV SFSVLTSCLA AYLFAFAGAF QMTIWALAKH RNYKKEFKDY PRQRRSIFPF 300
VL 302 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
 GO:0006629; P:lipid metabolic process; IEA:InterPro. 
Interpro
 IPR001104; 3-oxo-5_a-steroid_4-DH_C.
 IPR019955; Ubiquitin_supergroup. 
Pfam
 PF02544; Steroid_dh 
SMART
  
PROSITE
 PS50244; S5A_REDUCTASE
 PS50053; UBIQUITIN_2 
PRINTS