CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007269
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Conserved oligomeric Golgi complex subunit 3 
Protein Synonyms/Alias
 COG complex subunit 3; Component of oligomeric Golgi complex 3; Protein SEC34 
Gene Name
 COG3 
Gene Synonyms/Alias
 GRD20; SEC34; YER157W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
360FVEFFPEKECRFKINubiquitination[1]
Reference
 [1] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269
Functional Description
 Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis- Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events. COG3 is also involved in actin cytoskeleton organization. 
Sequence Annotation
 MOD_RES 507 507 Phosphoserine.
 MOD_RES 647 647 Phosphoserine.  
Keyword
 Complete proteome; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 801 AA 
Protein Sequence
MARSRKNSLV RDIASHPTIP ESQTIVGLLD DSYLFDKLKK LSLAVENSDS LQRTDVSEGC 60
SEVNGSEATT SADVKKTNKY LYYTTYLDQL NIKIDEYKVV LDQTRQVNDQ LDSSIKKFRK 120
ISQDTGAFIE ETKTIYEKQS KLSNLTESIP KALHYFEVLD PIMRRLNHAT SPAIVKKSSF 180
TTMLATIDES LRFLDENSDL KDAAAYRIKF KQCLIRACEL ISHFLTNLLK QTNQEILDKT 240
KNKNSLTGLP STTRDAFLYS KFYTIADTFK IQVSEIVKRS NEKAYNKYHD ELNSILYECF 300
NHYFQTRLRL LTPVIWSHID EIVVKDKDQG LVKFIQDGKV YFQQLCADEY KLFVEFFPEK 360
ECRFKINQWF LQLCEPLYDS IRVRVLKETD ICTLCDSVTL FAPYYEFEEG SEEYVKQFTD 420
IQYDKLFEPI VQKVQARLIL RVQIYVQQNI LSYRPTRDVF MISNRRRKSK TSLQGGNEDA 480
TTSDDNPDPL LESYLSSFKN RSILPISPND ADDKSIDSEE STDKISQLQT YYPPLLKTLA 540
LLSKIYEMIN SVVFDDLAHH VVHDCIVSLR NAYDMVIKSS AGKSDFNNLD ISLAYLKNLL 600
MLRDSIQNFN IQYTVNETYL DFSGVEGFFK SLKENGRNVL KKTKSSSILT LARELVPKVV 660
NNMVDARTEL ISELRNVIKD FTESTSLELI DDTLDINSDE DLLSKNVKLR ENIKARLPRI 720
YEQILNYIDD QEIVTNLLDA VQELITQSYS KYYETITELA ENGKFAKDQV ADVMYLDVFT 780
DFFAKEVADL LRNGDIDTIT K 801 
Gene Ontology
 GO:0005801; C:cis-Golgi network; IEA:InterPro.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0017119; C:Golgi transport complex; IPI:SGD.
 GO:0008565; F:protein transporter activity; TAS:SGD.
 GO:0032258; P:CVT pathway; IMP:SGD.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IGI:SGD.
 GO:0016236; P:macroautophagy; IMP:SGD.
 GO:0030242; P:peroxisome degradation; IMP:SGD.
 GO:0000301; P:retrograde transport, vesicle recycling within Golgi; IMP:SGD. 
Interpro
 IPR007265; COG_su3. 
Pfam
 PF04136; Sec34 
SMART
  
PROSITE
  
PRINTS