UniProt Accession

 G3UY38_MOUSE; G3UY38 

Genbank Protein ID

 AC171210 

Genbank Nucleotide ID

  

Protein Name

 Heterogeneous nuclear ribonucleoprotein L 

Protein Synonyms/Alias

  

Gene Name

 Hnrnpl 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
96	QRIVIFRKNGVQAMV	ubiquitination	[1]
136	TLKIEYAKPTRLNVF	ubiquitination	[1]
169	DPGSNPNKRQRQPPL	ubiquitination	[1]
278	CLYGNVEKVKFMKSK	acetylation	[2]
285	KVKFMKSKPGAAMVE	ubiquitination	[1]
322	KMNVCVSKQPAIMPG	acetylation	[2]
342	EDGSCSYKDFSESRN	acetylation	[2, 3]
360	STPEQAAKNRIQHPS	ubiquitination	[1]
400	VKRPTSVKVFSGKSE	ubiquitination	[1]
405	SVKVFSGKSERSSSG	acetylation	[3]
435	FLNHYQMKNPNGPYP	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 456 AA 

Protein Sequence

Gene Ontology

 GO:0045120; C:pronucleus; IDA:MGI.
 GO:0030529; C:ribonucleoprotein complex; IEA:Compara.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0044212; F:transcription regulatory region DNA binding; IEA:Compara.
 GO:0006397; P:mRNA processing; IEA:InterPro. 

Interpro

 IPR006536; HnRNP-L_PTB.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 

Pfam

  

SMART

 SM00360; RRM 

PROSITE

 PS50102; RRM 

PRINTS