CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001205
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcription initiation protein SPT3 homolog 
Protein Synonyms/Alias
 SPT3-like protein 
Gene Name
 SUPT3H 
Gene Synonyms/Alias
 SPT3 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
205EDDLLEDKLSGSNNAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 Probable transcriptional activator. 
Sequence Annotation
  
Keyword
 Activator; Alternative splicing; Complete proteome; Direct protein sequencing; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 399 AA 
Protein Sequence
MYSPRGSQGR GTAEATANSP SPPIAPSHSR VTFSLSTLHT LSPPPRPFPS VSRAAAQKPH 60
HLHPHILLAG SAAVPPRVLK AEMNNTAASP MSTATSSSGR STGKSISFAT ELQSMMYSLG 120
DARRPLHETA VLVEDVVHTQ LINLLQQAAE VSQLRGARVI TPEDLLFLMR KDKKKLRRLL 180
KYMFIRDYKS KIVKGIDEDD LLEDKLSGSN NANKRQKIAQ DFLNSIDQTG ELLAMFEDDE 240
IDEVKQERME RAERQTRIMD SAQYAEFCES RQLSFSKKAS KFRDWLDCSS MEIKPNVVAM 300
EILAYLAYET VAQLVDLALL VRQDMVTKAG DPFSHAISAT FIQYHNSAES TAACGVEAHS 360
DAIQPCHIRE AIRRYSHRIG PLSPFTNAYR RNGMAFLAC 399 
Gene Ontology
 GO:0030914; C:STAGA complex; IDA:UniProtKB.
 GO:0033276; C:transcription factor TFTC complex; IDA:UniProtKB.
 GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
 GO:0006352; P:DNA-dependent transcription, initiation; NAS:UniProtKB.
 GO:0016578; P:histone deubiquitination; IDA:UniProtKB.
 GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.
 GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
 GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. 
Interpro
 IPR009072; Histone-fold.
 IPR003195; TFIID-18. 
Pfam
 PF02269; TFIID-18kDa 
SMART
  
PROSITE
  
PRINTS