CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015508
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GPS, PLAT and transmembrane domain-containing protein FLJ00285 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
766KITPSARKPLCNRCTacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 DOMAIN 159 208 GPS.
 DOMAIN 265 379 PLAT.  
Keyword
 Alternative splicing; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 789 AA 
Protein Sequence
MAFQTQAGAQ IPIERLASER AITVKVPNNS DWAARGHRSS ANSVVVQPQA SVGAVVTLDS 60
SNPAAVLHLQ LNYTLLDGRY LSEEPEPYLA VYLHSEPRPN EHNCSASRRI RPESLQGADH 120
RPYTFFISPG TRDPVGSYRL NLSSHFRLSA LEVSVGLYTS LCQYFSEEDV VWRTEGLLPL 180
EETSPRQAVC LTRHLTAFGA SLFVPPSHVR FVFPEPTADV NYIVMLTCAV CLVTYMVMAA 240
ILHKLDQLDA SRGRAIPFCG QRGRFKYEIL VKTGWGRGSG TTAHVGIMLY GVDSRSGHRH 300
LDGDRAFHRN SLDIFRIATP HSLGSVWKIR VWHDKGLSPA WFLQHVIIRD LQTAHSTFFL 360
VNDWLSVETE ANGGLVEKEV LAASHAALLR FRRLLVAELQ CGFFDKHIWL SIWDRPPRSC 420
FTRIQRATCC VLLICLFLGA NAVWYGAVGD SAYSTGHVSR LSPLSVDTVA VGLVSSVVVY 480
PVYLAILFLF WMSRSKVAGS PSPTPAGQQV LDIDSCLDSS VLDSSFLTFS GLHAEVINTL 540
ADHRHRGTDF GGSPWLLIIT VFLRSYKFAI SLCTTYLWVI NTLADHRHRG TDFGGSPWLL 600
IITVFLRSYK FAISLCTTYL CVSFLKTIFP SQNGHDGSTD VQQRARRSNR RRQEGIKIVL 660
EDIFTLWRQV ETKVRAKIRK MKVTTKVNRH DKINGKRKTA KEHLRKLSMK EREHGEKERQ 720
VSEAEENGKL DMKEIHTYME MFQRAQALRR RAEDYYRCKI TPSARKPLCN RCTYNLVLPG 780
SEKKYYSHA 789 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro. 
Interpro
 IPR000203; GPS_dom.
 IPR008976; Lipase_LipOase.
 IPR001024; LipOase_LH2.
 IPR009443; NPIP.
 IPR000434; PKD_1. 
Pfam
 PF01825; GPS
 PF06409; NPIP
 PF01477; PLAT 
SMART
 SM00303; GPS
 SM00308; LH2 
PROSITE
 PS50221; GPS
 PS50095; PLAT 
PRINTS
 PR00500; POLYCYSTIN1.