CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024948
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Aox4 protein 
Protein Synonyms/Alias
  
Gene Name
 Aox4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
852GRHPLLGKYKIGFMNubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 2Fe-2S; Iron; Iron-sulfur; Metal-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1336 AA 
Protein Sequence
MPSVSESDEL IFFVNGKKVI EKNPDPEKNL LFYTRKVLNL TGTKYSCGTG GCGACTVMVS 60
RYNPKTRKIH HYPATACLVP ICWLHGAAIT TVEGVGSIKK RVHPVQERLA KCHGTQCGFC 120
SPGMVMSIYT LLRNHPEPTP DQITEALGGN LCRCTGYRPI VESGKTFSQK STVCQMKGSG 180
KCCMDPDEKC LESREKKMCT KLYNEDEFQP FDPSQEPIFP PELIRMAEDP NKRRLTFQGK 240
RTTWIIPVTL NDLLELKASY PEAPLVMGNT TVGPGIKFND EFYPVFISPL GVPELNLMDT 300
TNNGVTIGAG YSLAQLKDTL DFLVSEQPKE KTKTFHALQK HLRTLAGPQI RNMATLGGHT 360
ASRPNFSDLN PILAAGNATL NVVSREGKDR QLPLNGPFLE KLPEADLKPE EVILSIFIPY 420
TAQWQFVSGL RLAQRQENAF AIVNAGMSVE FEEGTNTIKD LKMFFGSVAP TVVSASQTCK 480
QLIGRQWDDQ MLSEACQLVL QEIRIPPDAE GGMVEYRRTL IISLLFKFYL KVQRWLNEMD 540
PQKFPDIPGK FVSALDDFPI ETPQGIQMFQ CVDPKQPQKD PVGHPIMHQS GIKHATGEAI 600
FIDDMPPIDQ ELCLAVVTST RAHAKITSLD VSEALACPGV VDVITAEDVP GENDHNGEIL 660
YAQSEVICVG QIICTVAADT YIHAKEAAKR VKIAYDDIEP TIITIEEALE HNSFLSPEKK 720
IEQGNVDYAF KHVDQIVEGE IHVEGQEHFY METQTILAIP QTEDKEMVLH LGTQFPTHVQ 780
EFVSAALNVP RSRIACHMKR AGGAFGGKVT KPALLGAVCA VAANKTGRPI RFILERSDDM 840
LITAGRHPLL GKYKIGFMNN GEIRAADVEY YTNGGCTPDE SELVIEFVVL KSENTYHIPN 900
FRCRGRACKT NLPSNTAFRG FGFPQATVVV EAYIAAVASK CNLLPEEVRE INMYKKTSKT 960
AYKQTFNPEP LRRCWKECLE KSSFFARKKA AEEFNGNNYW KKRGLAVVPM KFSVAVPIAF 1020
YNQAAALVHI FLDGSVLLTH GGCELGQGLH TKMIQVASRE LNVPKSYVHF SETSTTTVPN 1080
SAFTAGSMGA DINGKAVQNA CQILMDRLRP IIRKNPKGKW EEWIKMAFEE SISLSATGYF 1140
KGYQTNMDWK KEEGDPYPYY VYGAACSEVE VDCLTGAHKL LRTDIFVDAA FSINPALDIG 1200
QVEGAFIQGM GFYTTEELKY SPKGVLYSRG PEDYKIPTVT EIPEEFYVTL VHSRNPIAIY 1260
SSKGLGEAGM FLGSSVLFAI YDAVTTARKE RGLSDIFPLN SPATPEVIRM ACTDQFTEMI 1320
PRDDPSTFTP WSIHVS 1336 
Gene Ontology
 GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
 GO:0004031; F:aldehyde oxidase activity; ISA:MGI.
 GO:0009055; F:electron carrier activity; ISA:MGI.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0030151; F:molybdenum ion binding; ISA:MGI.
 GO:0051287; F:NAD binding; IEA:InterPro.
 GO:0008762; F:UDP-N-acetylmuramate dehydrogenase activity; IEA:InterPro. 
Interpro
 IPR002888; 2Fe-2S-bd.
 IPR001041; 2Fe-2S_ferredoxin-type.
 IPR006058; 2Fe2S_fd_BS.
 IPR000674; Ald_Oxase/Xan_DH_a/b.
 IPR016208; Ald_Oxase/xanthine_DH.
 IPR014313; Aldehyde_oxidase.
 IPR008274; AldOxase/xan_DH_Mopterin-bd.
 IPR012675; Beta-grasp_dom.
 IPR005107; CO_DH_flav_C.
 IPR016169; CO_DH_flavot_FAD-bd_sub2.
 IPR016166; FAD-bd_2.
 IPR016167; FAD-bd_2_sub1.
 IPR002346; Mopterin_DH_FAD-bd. 
Pfam
 PF01315; Ald_Xan_dh_C
 PF02738; Ald_Xan_dh_C2
 PF03450; CO_deh_flav_C
 PF00941; FAD_binding_5
 PF00111; Fer2
 PF01799; Fer2_2 
SMART
 SM01008; Ald_Xan_dh_C
 SM01092; CO_deh_flav_C 
PROSITE
 PS00197; 2FE2S_FER_1
 PS51085; 2FE2S_FER_2
 PS51387; FAD_PCMH 
PRINTS