| Tag | Content |
|---|
| CPLM ID | CPLM-019715 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | D-aspartate oxidase |
Protein Synonyms/Alias | DASOX; DDO |
Gene Name | DDO |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 118 | DVVLGFRKMTEAELK | ubiquitination | [1] | | 125 | KMTEAELKKFPQYVF | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. |
Sequence Annotation | NP_BIND 6 20 FAD (By similarity).
NP_BIND 36 37 FAD (By similarity).
NP_BIND 43 44 FAD (By similarity).
NP_BIND 48 50 FAD (By similarity).
NP_BIND 307 311 FAD (By similarity).
MOTIF 339 341 Microbody targeting signal (Potential).
BINDING 166 166 FAD; via amide nitrogen and carbonyl
BINDING 183 183 FAD (By similarity).
BINDING 223 223 Substrate (By similarity).
BINDING 278 278 Substrate (By similarity).
BINDING 312 312 FAD (By similarity). |
Keyword | Alternative splicing; Complete proteome; FAD; Flavoprotein; Oxidoreductase; Peroxisome; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 341 AA |
Protein Sequence | MDTARIAVVG AGVVGLSTAV CISKLVPRCS VTIISDKFTP DTTSDVAAGM LIPHTYPDTP 60
IHTQKQWFRE TFNHLFAIAN SAEAGDAGVH LVSGWQIFQS TPTEEVPFWA DVVLGFRKMT 120
EAELKKFPQY VFGQAFTTLK CECPAYLPWL EKRIKGSGGW TLTRRIEDLW ELHPSFDIVV 180
NCSGLGSRQL AGDSKIFPVR GQVLQVQAPW VEHFIRDGSG LTYIYPGTSH VTLGGTRQKG 240
DWNLSPDAEN SREILSRCCA LEPSLHGACN IREKVGLRPY RPGVRLQTEL LARDGQRLPV 300
VHHYGHGSGG ISVHWGTALE AARLVSECVH ALRTPIPKSN L 341 |
Gene Ontology | GO:0005777; C:peroxisome; NAS:UniProtKB. GO:0048037; F:cofactor binding; IDA:UniProtKB. GO:0003884; F:D-amino-acid oxidase activity; IEA:InterPro. GO:0008445; F:D-aspartate oxidase activity; IDA:UniProtKB. GO:0006533; P:aspartate catabolic process; IDA:UniProtKB. GO:0006531; P:aspartate metabolic process; IEA:Compara. GO:0019478; P:D-amino acid catabolic process; IDA:UniProtKB. GO:0007625; P:grooming behavior; IEA:Compara. GO:0042445; P:hormone metabolic process; IEA:Compara. GO:0007320; P:insemination; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |