CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027455
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 26S proteasome subunit, putative 
Protein Synonyms/Alias
  
Gene Name
 PF14_0632 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
1112RVIKMQEKYIEYIPNacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Proteasome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1172 AA 
Protein Sequence
MRFENQFSKH DIVTSASGVI ALLNEEETSL KLFGLEKLNA IVDVYWPELA DSIFKIEELC 60
EDEDFVGREL ANLLASKIYF HLEKYSEALK YALCAGKLFN IKEKSQYVET MLAKCIEKYV 120
EIREMQYDID YNNQHNINDG ITNNNDIFNA YNNNDLVELN SHNELLNKET DIFRFDINNE 180
INQKMELLVD EMIDVCIKSN DIKEALGVAL DARRLDKVEY IIANAENKIE ILAHSINNEK 240
HINMNKSFRN EYFKLLVNLY LSLSEEELKT EYINLCECLY YIDDYKKVAE ILLKLLHNYH 300
LMAYQISFDL VDFENKIFLR NILGQIKENL IQNKAYYFGE EYFVTTPQEE NNDADNKENE 360
SNAITNEQQD ENNNEKEDKD NNDGKNPEHN DDNNKPNDNL TNDEPTYNNN DDKAINDGND 420
NDNNNNNNIN NNNNNIVEDV LKYISKKHIF YNKMKKLLYI LTGKVTGNLY IEFLHRNNHA 480
DLILLDTYKN IVDSRSSITH HGIVIAHALM QTGTTCDVFL RSNIEWLSKA INWEKFSATA 540
SLGVVYKGHV NESFMVLSTH LPYNDVSTEI ANNINVGLAP SGVYSEGGSL YALGLIHANY 600
NTNDKKVKNY LMSQLKSNMN DEVLQHGCCL GLGLVCLGDS NDENTYDELK AILYSDSAVA 660
GESAAYAIGL LKLGSGDDKC IDELLAYAHD TQHEKITRAC SISLGFVMFQ KEREADSLIE 720
ELVSDKDAII RYGGMFAIAM AYCGLSNCNK HIIKKLLHFS VSDVSDDVRR AAVIALGFVL 780
CNSPNQVPKF LNLLIESYNP HVRYGAALAL GIACSATANE EAINMLMPLL TDTTDFVRQS 840
AFISLGLIFQ QSNEHCNPNF KKYKEEIMKI LSDKHEDIIA KFGAIVSAGL LDICGRNAIS 900
TFFTRRGNII RPQAAAGFCL FSQLWYWFPL IHMISLTFMP TCLIGLTEDL KVPKNFSILS 960
TSNNQNFDYP SFLSKEKTQE KKETVTAVLS TTAKRKTLKL KKQKNDSKIT KERTAQDDNS 1020
SVLSDGKSMK NLEILSTAAT IGQSSHVSHA ESVEGSANDE NSHDHAQDGS NISNVQKGKK 1080
SEAKSKSGAN ENSNNNTVDM KNPCRVIKMQ EKYIEYIPNS RYIPVLPTRK SGFIMLNDIT 1140
PLEPSECIEI NFEETSKKEA PPFEPFSWKE EN 1172 
Gene Ontology
 GO:0005838; C:proteasome regulatory particle; ISS:GeneDB_Pfalciparum.
 GO:0004175; F:endopeptidase activity; ISS:GeneDB_Pfalciparum.
 GO:0030234; F:enzyme regulator activity; IEA:InterPro.
 GO:0050790; P:regulation of catalytic activity; IEA:GOC.
 GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:GeneDB_Pfalciparum. 
Interpro
 IPR016642; 26S_Psome_Rpn2.
 IPR002015; APC_proteasome.
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR004155; PBS_lyase_HEAT. 
Pfam
 PF01851; PC_rep 
SMART
 SM00567; EZ_HEAT 
PROSITE
  
PRINTS