CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030926
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Arginyl-tRNA--protein transferase 1 
Protein Synonyms/Alias
 Arginyltransferase 1; R-transferase 1; Arginine-tRNA--protein transferase 1 
Gene Name
 ATE1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
154LPENASHKLEVRVVRubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity). 
Sequence Annotation
  
Keyword
 Acyltransferase; Complete proteome; Reference proteome; Transferase; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 403 AA 
Protein Sequence
MDSTMDDAVA GDFALINKLD IQCDLKTLSD DIKESLESEG KNSKKEEPQE LLQSQDFVGE 60
KLGSGEPSHS VKVHTVPKPG KGADLSKPPC RKAKEIRKER KRLKLMQQNP AGELEGFQAQ 120
GHPPSLFPPK AKSNQPKSLE DLIFESLPEN ASHKLEVRVV RSSPPSSQFK ATLLESYQVY 180
KRYQMVIHKN PPDTPTESQF TRFLCSSPLE AETPPNGPDC GYGSFHQQYW LDGKIIAVGV 240
IDILPNCVSS VYLYYDPDYS FLSLGVYSAL REIAFTRQLH EKTSQLSYYY MGFYIHSCPK 300
MKYKGQYRPS DLLCPETYVW VPIEQCLPSL ENSKYCRFNQ DPEAVDEDRS TEPDRLQVFH 360
KRAIMPYGVY KKQQKDPSEE AAVLQYASLV GQKCSERMLL FRN 403 
Gene Ontology
 GO:0004057; F:arginyltransferase activity; IEA:EC.
 GO:0016598; P:protein arginylation; IEA:InterPro. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR017137; Arg-tRNA-P_Trfase_1_euk.
 IPR007472; Arg-tRNA-P_Trfase_C. 
Pfam
 PF04377; ATE_C 
SMART
  
PROSITE
  
PRINTS