CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012800
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serum response factor homolog 
Protein Synonyms/Alias
 dSRF; Protein blistered 
Gene Name
 bs 
Gene Synonyms/Alias
 Serf; CG3411 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
440KNDASADKPLTIKQEacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 Required for the formation of intervein tissue of the wing. Acts in a dosage-dependent manner to suppress wing vein formation and promote development of intervein cells. Might play a role in the proper formation and maintenance of the trachea. 
Sequence Annotation
 DOMAIN 167 225 MADS-box.
 MOD_RES 156 156 Phosphoserine.  
Keyword
 Activator; Complete proteome; Developmental protein; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 449 AA 
Protein Sequence
MDPTRGDSRY NLNYSMSSIG LSLADPADMY GNPALGAGRP PSGGLLQNMG GVPPMQRPNP 60
AAGAPPAPQC QTLHSPQHAS QQQQQQQQQQ QQHQQQQQQQ QQHPQQQRGL KRSGSDCYED 120
HHRSSGGLTL QGLDNVASGA VDDSVDNYNP LPNKKSPPAN GKKTKGRVKI KMEYIDNKLR 180
RYTTFSKRKT GIMKKAYELS TLTGTQVMLL VASETGHVYT FATRKLQPMI TSEAGKQLIQ 240
TCLNSPDPPS VGGGDQRMSA TGFEETELSY NIADEDSKDD RSPTSSGNES DDSSDVEMPA 300
EAAEVATKLP ASKTEVSAPP AASCSAATAS SGHKTMPALN YQTDTNSGPS TSTAAGGGGS 360
ADSKYVYSAA SIANIPQKML RQLIQSGHLQ VHAEEDGNQY VTIPLSSTAA NLIKSNKLTA 420
SGSGASGSGT PVKNDASADK PLTIKQEFD 449 
Gene Ontology
 GO:0005634; C:nucleus; IDA:FlyBase.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0007475; P:apposition of dorsal and ventral imaginal disc-derived wing surfaces; IMP:FlyBase.
 GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.
 GO:0002168; P:instar larval development; IMP:UniProtKB.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.
 GO:0035209; P:pupal development; IMP:UniProtKB.
 GO:0030431; P:sleep; IMP:FlyBase.
 GO:0007430; P:terminal branching, open tracheal system; IMP:FlyBase.
 GO:0035154; P:terminal cell fate specification, open tracheal system; TAS:FlyBase.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR002100; TF_MADSbox. 
Pfam
 PF00319; SRF-TF 
SMART
 SM00432; MADS 
PROSITE
 PS00350; MADS_BOX_1
 PS50066; MADS_BOX_2 
PRINTS
 PR00404; MADSDOMAIN.