UniProt Accession

 FCGRC_HUMAN; A6NKC4 

Genbank Protein ID

 AL109948 

Genbank Nucleotide ID

  

Protein Name

 Putative high affinity immunoglobulin gamma Fc receptor IC 

Protein Synonyms/Alias

 IgG Fc receptor IC; Fc-gamma RIC; FcRIC; hFcgammaRIC 

Gene Name

 FCGR1C 

Gene Synonyms/Alias

 IGFRC 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
228	KELKRKKKWNLEISL	acetylation	[1]
241	SLDSGHEKKVISSLQ	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

 May bind to the Fc region of immunoglobulins gamma. May function in the humoral immune response (By similarity). 

Sequence Annotation

 DOMAIN 22 101 Ig-like C2-type 1.
 DOMAIN 105 182 Ig-like C2-type 2.
 CARBOHYD 59 59 N-linked (GlcNAc...) (Potential).
 CARBOHYD 152 152 N-linked (GlcNAc...) (Potential).
 CARBOHYD 163 163 N-linked (GlcNAc...) (Potential).
 DISULFID 43 85 By similarity.
 DISULFID 124 168 By similarity.  

Keyword

 Adaptive immunity; Cell membrane; Complete proteome; Disulfide bond; Glycoprotein; IgG-binding protein; Immunity; Immunoglobulin domain; Membrane; Polymorphism; Receptor; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 280 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub.
 IPR003598; Ig_sub2. 

Pfam

  

SMART

 SM00409; IG
 SM00408; IGc2 

PROSITE

 PS50835; IG_LIKE 

PRINTS