UniProt Accession

 THY1_RAT; P01830 

Genbank Protein ID

 X03152; X03150; X02002; M18002; M10666 

Genbank Nucleotide ID

 CAA26931.1; CAA26929.1; CAA26033.1; AAA42243.1; AAA42242.1 

Protein Name

 Thy-1 membrane glycoprotein 

Protein Synonyms/Alias

 Thy-1 antigen; CD90 

Gene Name

 Thy1 

Gene Synonyms/Alias

 Thy-1 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
59	FSLTREKKKHVLSGT	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. 

Sequence Annotation

 DOMAIN 20 126 Ig-like V-type.
 MOD_RES 20 20 Pyrrolidone carboxylic acid.
 LIPID 130 130 GPI-anchor amidated cysteine.
 CARBOHYD 42 42 N-linked (GlcNAc...) (high mannose or
 CARBOHYD 42 42 N-linked (GlcNAc...) (high mannose); in
 CARBOHYD 93 93 N-linked (GlcNAc...) (complex).
 CARBOHYD 117 117 N-linked (GlcNAc...) (complex); in
 CARBOHYD 117 117 N-linked (GlcNAc...) (high mannose or
 DISULFID 28 130
 DISULFID 38 104  

Keyword

 Cell membrane; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; GPI-anchor; Immunoglobulin domain; Lipoprotein; Membrane; Pyrrolidone carboxylic acid; Reference proteome; Sialic acid; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 161 AA 

Protein Sequence

Gene Ontology

 GO:0031362; C:anchored to external side of plasma membrane; IEA:Compara.
 GO:0046658; C:anchored to plasma membrane; IDA:RGD.
 GO:0016324; C:apical plasma membrane; IEA:Compara.
 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0030425; C:dendrite; IEA:Compara.
 GO:0005783; C:endoplasmic reticulum; IEA:Compara.
 GO:0009897; C:external side of plasma membrane; ISS:UniProtKB.
 GO:0030426; C:growth cone; IDA:UniProtKB.
 GO:0045121; C:membrane raft; IEA:Compara.
 GO:0034235; F:GPI anchor binding; IDA:UniProtKB.
 GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.
 GO:0001525; P:angiogenesis; ISS:UniProtKB.
 GO:0016337; P:cell-cell adhesion; IMP:UniProtKB.
 GO:0007010; P:cytoskeleton organization; IDA:UniProtKB.
 GO:0048041; P:focal adhesion assembly; IDA:UniProtKB.
 GO:0045576; P:mast cell activation; NAS:UniProtKB.
 GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
 GO:0050771; P:negative regulation of axonogenesis; IDA:UniProtKB.
 GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
 GO:0048147; P:negative regulation of fibroblast proliferation; NAS:UniProtKB.
 GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.
 GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:UniProtKB.
 GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; NAS:UniProtKB.
 GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:UniProtKB.
 GO:0050870; P:positive regulation of T cell activation; IDA:UniProtKB.
 GO:0046549; P:retinal cone cell development; ISS:UniProtKB.
 GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub.
 IPR013151; Immunoglobulin. 

Pfam

 PF00047; ig 

SMART

 SM00409; IG 

PROSITE

 PS50835; IG_LIKE 

PRINTS