CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043199
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Epidermal growth factor receptor substrate 15 
Protein Synonyms/Alias
  
Gene Name
 Eps15 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
485SYEEELLKAREELSRubiquitination[1]
508EESVESGKAQLEPLQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 933 AA 
Protein Sequence
MAAAAQLSLT QLSSGNPVYE KYYRQVEAGN TGRVLALDAA AFLKKSGLPD LILGKIWDLA 60
DTDGKGVLSK QEFFVALRLV ACAQNGLEVS LSSLSLAVPP PRFHDSSSPL LTSGPSVAEL 120
PWAVKSEDKA KYDAIFDSLS PVDGFLSGDK VKPVLLNSKL PVEILGRVWE LSDIDHDGKL 180
DRDEFAVAMF LVYCALEKEP VPMSLPPALV PPSKRKTVSI SGSKWVIPSS AAKESYHSLP 240
PVGISPTKAP LRQWVVSPAE KAKYDEIFLK TDKDMDGYVS GLEVRETFLK TGLPSALLAH 300
IWSLCDTKGC GKLSKDQFAL AFHLINQKLI KGIDPPHSLT PEMIPPSDRS SLQKNITGSS 360
PVADFSAIKE LDTLNNEIVD LQREKNNVEQ DLKEKEDTVK QRTSEVQDLQ DEVQRESINL 420
QKLQAQKQQV QELLGELDEQ KAQLEEQLQE VRKKCAEEAQ LISSLKAEIT SQESQISSYE 480
EELLKAREEL SRLQQETAQL EESVESGKAQ LEPLQQHLQE SQQEISSMQM RLEMKDLETD 540
NNQSNWSSSP QSVLVNGATD YCSLSTSSSE TANFNEHAEG QNNLESEPTH QESSVRSSPE 600
IAPSDVTDES EAVTVAGNEK VTPRFDDDKH SKEEDPFNVE SSSLTDAVAD TNLDFFQSDP 660
FVGSDPFKDD PFGKIDPFGG DPFKGSDPFA SDCFFKQTST DPFTTSSTDP FSASSNSSNT 720
SVETWKHNDP FAPGGTVVAA ASDSATDPFA SVFGNESFGD GFADFSTLSK VNNEDAFNPT 780
ISSSTSSVTI AKPMLEETAS KSEDVPPALP PKVGTPTRPC PPPPGKRPIN KLDSSDPLKL 840
NDPFQPFPGN DSPKEKDPDM FCDPFTSSTT TNKEADPSNF ANFSAYPSEE DMIEWAKRES 900
EREEEQRLAR LNQQEQEDLE LAIALSKSEI SEA 933 
Gene Ontology
 GO:0060170; C:cilium membrane; IDA:MGI.
 GO:0005905; C:coated pit; IDA:MGI.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR000261; EPS15_homology.
 IPR003903; Ubiquitin-int_motif. 
Pfam
  
SMART
 SM00054; EFh
 SM00027; EH
 SM00726; UIM 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS50031; EH
 PS50330; UIM 
PRINTS