UniProt Accession

 ARL11_HUMAN; Q969Q4 

Genbank Protein ID

 AF441378; AK091249; AL135901; BC013150 

Genbank Nucleotide ID

 AAP19650.1; BAC03621.1; CAI40715.1; AAH13150.1 

Protein Name

 ADP-ribosylation factor-like protein 11 

Protein Synonyms/Alias

 ADP-ribosylation factor-like tumor suppressor protein 1 

Gene Name

 ARL11 

Gene Synonyms/Alias

 ARLTS1 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
31	GKTTLLYKLKGHQLV	acetylation	[1]
31	GKTTLLYKLKGHQLV	ubiquitination	[2, 3]

Reference

 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

 May play a role in apoptosis. May act as a tumor suppressor. 

Sequence Annotation

 NP_BIND 19 26 GTP (By similarity).
 NP_BIND 63 67 GTP (By similarity).
 NP_BIND 122 125 GTP (By similarity).
 LIPID 2 2 N-myristoyl glycine (Potential).  

Keyword

 Complete proteome; GTP-binding; Lipoprotein; Myristate; Nucleotide-binding; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 196 AA 

Protein Sequence

Gene Ontology

 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR024156; Small_GTPase_ARF.
 IPR006689; Small_GTPase_ARF/SAR. 

Pfam

 PF00025; Arf 

SMART

 SM00177; ARF 

PROSITE

 PS51417; ARF 

PRINTS

 PR00328; SAR1GTPBP.