UniProt Accession

 G3UXI6_MOUSE; G3UXI6 

Genbank Protein ID

 CR974444 

Genbank Nucleotide ID

  

Protein Name

 Spliceosome RNA helicase Ddx39b 

Protein Synonyms/Alias

  

Gene Name

 Ddx39b 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
56	KEYERFSKYMPNVKV	acetylation	[1]
73	FFGGLSIKKDEEVLK	ubiquitination	[2]
106	RNKSLNLKHIKHFIL	acetylation	[3]
109	SLNLKHIKHFILDEC	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 148 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005681; C:spliceosomal complex; IEA:Compara.
 GO:0000346; C:transcription export complex; IEA:Compara.
 GO:0005687; C:U4 snRNP; IEA:Compara.
 GO:0005688; C:U6 snRNP; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004004; F:ATP-dependent RNA helicase activity; IEA:Compara.
 GO:0030621; F:U4 snRNA binding; IEA:Compara.
 GO:0017070; F:U6 snRNA binding; IEA:Compara.
 GO:0046784; P:intronless viral mRNA export from host nucleus; IEA:Compara.
 GO:0010501; P:RNA secondary structure unwinding; IEA:Compara.
 GO:0000245; P:spliceosomal complex assembly; IEA:Compara. 

Interpro

 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR014001; Helicase_ATP-bd.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00270; DEAD 

SMART

 SM00487; DEXDc 

PROSITE

 PS51192; HELICASE_ATP_BIND_1 

PRINTS