CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003268
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sulfurtransferase TusE 
Protein Synonyms/Alias
 tRNA 2-thiouridine synthesizing protein E 
Gene Name
 tusE 
Gene Synonyms/Alias
 yccK; b0969; JW0952 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
68PAIRMLVKAMANKFGacetylation[1]
73LVKAMANKFGEEKGNacetylation[1]
78ANKFGEEKGNSRYLYacetylation[1]
104TKIAGLPKPVKCI**acetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD. 
Sequence Annotation
 ACT_SITE 108 108 Cysteine persulfide intermediate.  
Keyword
 Complete proteome; Cytoplasm; Reference proteome; Transferase; tRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 109 AA 
Protein Sequence
MLIFEGKEIE TDTEGYLKES SQWSEPLAVV IAENEGISLS PEHWEVVRFV RDFYLEFNTS 60
PAIRMLVKAM ANKFGEEKGN SRYLYRLFPK GPAKQATKIA GLPKPVKCI 109 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0097163; F:sulfur carrier activity; IDA:EcoCyc.
 GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
 GO:0002143; P:tRNA wobble position uridine thiolation; IMP:EcoCyc. 
Interpro
 IPR025526; DsrC-like_dom.
 IPR007453; DsrC/TusE. 
Pfam
 PF04358; DsrC 
SMART
  
PROSITE
  
PRINTS