UniProt Accession

 KV312_HUMAN; P18135 

Genbank Protein ID

  

Genbank Nucleotide ID

  

Protein Name

 Ig kappa chain V-III region HAH 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
124	RTFGQGTKVEIKR**	glycation	[1]

Reference

 [1] Proteomic profiling of nonenzymatically glycated proteins in human plasma and erythrocyte membranes.
 Zhang Q, Tang N, Schepmoes AA, Phillips LS, Smith RD, Metz TO.
 J Proteome Res. 2008 May;7(5):2025-32. [PMID: 18396901] 

Functional Description

  

Sequence Annotation

 REGION 21 43 Framework-1.
 REGION 44 55 Complementarity-determining-1.
 REGION 56 70 Framework-2.
 REGION 71 77 Complementarity-determining-2.
 REGION 78 109 Framework-3.
 REGION 110 118 Complementarity-determining-3.
 REGION 119 129 JK1 segment.
 DISULFID 43 109 By similarity.  

Keyword

 3D-structure; Complete proteome; Disulfide bond; Immunoglobulin domain; Immunoglobulin V region; Reference proteome; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 129 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; NAS:UniProtKB.
 GO:0005886; C:plasma membrane; TAS:Reactome.
 GO:0003823; F:antigen binding; NAS:UniProtKB.
 GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
 GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
 GO:0045087; P:innate immune response; TAS:Reactome. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013106; Ig_V-set.
 IPR003596; Ig_V-set_subgr. 

Pfam

 PF07686; V-set 

SMART

 SM00406; IGv 

PROSITE

 PS50835; IG_LIKE 

PRINTS