CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037990
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Eps15 
Protein Synonyms/Alias
  
Gene Name
 Eps15 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
227VSPAEKAKYDEIFLKacetylation[1]
413AQLEEQLKEVRKKCAubiquitination[2]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 792 AA 
Protein Sequence
MAAAAQLSLT QLSSGNPVYE KYYRQVEAGN TGRVLALDAA AFLKKSGLPD LILGKIWDLA 60
DTDGKGVLNK QEFFIALRLV ACAQNGLEVS LSSLNLAVPP PRFHDSSSPL LTSGTSVAEL 120
PWAVKSEDKA KYDAIFDSLS PVDGFLSGDK VKPVLLNSKL PVEILGRVWE LSDIDHDGKL 180
DRDEFAVAMF LVYCALEKEP VPMSLPPALV PPSKRKTWVV SPAEKAKYDE IFLKTDKDMD 240
GYVSGLEVRE TFLKTGLPST LLAHIWALCD TKNCGKLSKD QFALAFHLIN QKLIKGIDPP 300
HSLTPEMIPP SDKSSLQKNT IGSSPVADFS AIKELDTLNN EIIDLQREKN NVEQDLKEKE 360
DTVRQRTTEA QDLQDEVQRE SLNLQKLQAQ KQQVQELLDE LDEQKAQLEE QLKEVRKKCA 420
EEAQLISSLK AEITSQESQI STYEEELSKA REELSRLQQE TAQLEESVES GKAQLEPLQQ 480
HLQDSQQEIS SMQMRLAMKD LETDNNQSNW CSSPQSILVN GAADYCSLST SSSETANLNE 540
HAEGQNNLES EPIHPESSVR SSPEIAPSDV TDESEVVTAA DIEKVSPRFD DDKHSKEEDP 600
FNVESGSMTN AVPDPTLYFF QSAPFVASDP FKDDPFGKID PFGGDPFKGS DPFASDCFFK 660
QTSTDPFATS STDPFSASSN SSNTSVETWK HNDPFAPGGT VVAATDSATD PFASVFGNES 720
FGDGFADFST LSKVSNEDPF NPTISSSASS VVIPKPVLEE TPSKSEDVPP ALPPKTGTPT 780
RPCPPPPAFP RQ 792 
Gene Ontology
 GO:0030122; C:AP-2 adaptor complex; IEA:Compara.
 GO:0060170; C:cilium membrane; IEA:Compara.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0048268; P:clathrin coat assembly; IEA:Compara. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR000261; EPS15_homology. 
Pfam
  
SMART
 SM00054; EFh
 SM00027; EH 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS50031; EH 
PRINTS