UniProt Accession

 TPC6A_HUMAN; O75865; K7ERB1; K7ERQ4; Q9BQ45; Q9P092 

Genbank Protein ID

 AF161407; AC005757; BC001907; BC004450 

Genbank Nucleotide ID

 AAF28967.1; AAC62259.1; AAH01907.1; AAH04450.1 

Protein Name

 Trafficking protein particle complex subunit 6A 

Protein Synonyms/Alias

 TRAPP complex subunit 6A 

Gene Name

 TRAPPC6A 

Gene Synonyms/Alias

 HSPC289 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
80	LWVAVFQKQMDSLRT	ubiquitination	[1]
158	KFQVVIPKS******	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

 May play a role in vesicular transport during the biogenesis of melanosomes (By similarity). 

Sequence Annotation

  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 159 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. 

Interpro

 IPR024096; NO_sig/Golgi_transp_ligand-bd.
 IPR007194; TRAPP_component. 

Pfam

 PF04051; TRAPP 

SMART

  

PROSITE

  

PRINTS