CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020454
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 407 
Protein Synonyms/Alias
  
Gene Name
 ZNF407 
Gene Synonyms/Alias
 KIAA1703 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
680ESMDDSGKASQEEPLubiquitination[1]
688ASQEEPLKSRVSHGNubiquitination[1]
1364DSSIIRIKNPEDGELubiquitination[1]
1703GTRHALTKHRRQHTGubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 ZN_FING 186 208 C2H2-type 1.
 ZN_FING 215 238 C2H2-type 2.
 ZN_FING 244 268 C2H2-type 3.
 ZN_FING 528 551 C2H2-type 4.
 ZN_FING 557 581 C2H2-type 5.
 ZN_FING 615 639 C2H2-type 6.
 ZN_FING 705 728 C2H2-type 7.
 ZN_FING 850 873 C2H2-type 8.
 ZN_FING 879 903 C2H2-type 9.
 ZN_FING 1017 1040 C2H2-type 10.
 ZN_FING 1046 1070 C2H2-type 11.
 ZN_FING 1444 1468 C2H2-type 12.
 ZN_FING 1486 1509 C2H2-type 13.
 ZN_FING 1537 1561 C2H2-type 14; degenerate.
 ZN_FING 1567 1589 C2H2-type 15.
 ZN_FING 1595 1618 C2H2-type 16.
 ZN_FING 1628 1650 C2H2-type 17.
 ZN_FING 1656 1680 C2H2-type 18.
 ZN_FING 1686 1708 C2H2-type 19.
 ZN_FING 1714 1736 C2H2-type 20.
 ZN_FING 1742 1767 C2H2-type 21.
 ZN_FING 1773 1796 C2H2-type 22.  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2248 AA 
Protein Sequence
MMDSENKPEN DEDEKINKEA QDLTKLSSHN EDGGPVSDVI ASFPENSMGK RGFSESSNSD 60
SVVIGEDRNK HASKRRKLDE AEPLKSGKQG ICRLETSESS VTEGGIALDE TGKETFLSDC 120
TVGGTCLPNA LSPSCNFSTI DVVSLKTDTE KTSAQEMVSL DLERESPFPP KEISVSCTIG 180
NVDTVLKCSI CGHLFSSCSD LEKHAESHMQ QPKEHTCCHC SHKAESSSAL HMHIKQAHGP 240
QKVFSCDLCG FQCSEENLLN AHYLGKTHLR RQNLAARGGF VQILTKQPFP KKSRTMATKN 300
VHSKPRTSKS IAKNSDSKGL RNVGSTFKDF RGSISKQSGS SSELLVEMMP SRNTLSQEVE 360
IVEEHVTSLG LAQNPENQSR KLDTLVTSEG LLEKLESTKN TLQAAHGNSV TSRPRPERNI 420
LVLGNSFRRR SSTFTLKGQA KKRFNLLGIK RGTSETQRMY MKHLRTQMKT HDAESVLKHL 480
EACSSVQRVC VTTSETQEAE QGQGSARPPD SGLHSLTVKP ASGSQTLCAC TDCGQVATNR 540
TDLEIHVKRC HAREMKFYCR TCDFSSMSRR DLDEHLHSNQ HQQTASVLSC QCCSFISLDE 600
INLRDHMKEK HNMHFLCTPC NLFFLSEKDV EEHKATEKHI NSLVQPKTLQ SSNSDLVLQT 660
LPLSTLESEN AKESMDDSGK ASQEEPLKSR VSHGNEVRHS SKPQFQCKKC FYKTRSSTVL 720
TRHIKLRHGQ DYHFLCKACN LYSLSKEGME KHIKRSKHLE NAKKNNIGLS FEECIERVCI 780
GANDKKEEFD VSGNGRIEGH IGVQLQEHSY LEKGMLASEE LSQSGGSTKD DELASTTTPK 840
RGRPKGNISR TCSHCGLLAS SITNLTVHIR RKHSHQYSYL CKVCKYYTVT KGDMERHCAT 900
KKHKGRVEIE ASGKHSSDII VGPEGGSLEA GKKNAGSAVT MSDEHANKPA ESPTSVLEKP 960
DRGNSIEAEV ENVFHSLDGE VNSHLLDKKE QISSEPEDFA QPGDVYSQRD VTGTGENKCL 1020
HCEFSAHSSA SLELHVKRKH TKEFEFYCMA CDYYAVTRRE MTRHAATEKH KMKRQSYLNS 1080
ANVEAGSADM SKNIIMPEEE HQQNSEEFQI ISGQPSDTLK SRNAADCSIL NENTNLDMSK 1140
VLCAADSVEV ETEEESNFNE DHSFCETFQQ APVKDKVRKP EEMMSLTMSS NYGSPSRFQN 1200
ENSGSSALNC ETAKKNHEIS NDAGELRVHC EGEGGNAGDG GGVVPHRHLC PVTLDGERSA 1260
ESPVLVVTRI TREQGNLESG GQNRVARGHG LEDLKGVQED PVLGNKEILM NSQHETEFIL 1320
EEDGPASDST VESSDVYETI ISIDDKGQAM YSFGRFDSSI IRIKNPEDGE LIDQSEEGLI 1380
ATGVRISELP LKDCAQGVKK KKSEGSSIGE STRIRCDDCG FLADGLSGLN VHIAMKHPTK 1440
EKHFHCLLCG KSFYTESNLH QHLASAGHMR NEQASVEELP EGGATFKCVK CTEPFDSEQN 1500
LFLHIKGQHE ELLREVNKYI VEDTEQINRE REENQGNVCK YCGKMCRSSN SMAFLAHIRT 1560
HTGSKPFKCK ICHFATAQLG DARNHVKRHL GMREYKCHVC GVAFVMKKHL NTHLLGKHGV 1620
GTPKERKFTC HLCDRSFTEK WALNNHMKLH TGEKPFKCTW PTCHYSFLTA SAMKDHYRTH 1680
TGEKSFLCDL CGFAGGTRHA LTKHRRQHTG EKPFKCDECN FASTTQSHLT RHKRVHTGEK 1740
PYRCPWCDYR SNCAENIRKH ILHTGKHEGV KMYNCPKCDY GTNVPVEFRN HLKEQHPDIE 1800
NPDLAYLHAG KGQKL 1815 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd.
 IPR003604; Znf_U1. 
Pfam
 PF00096; zf-C2H2 
SMART
 SM00355; ZnF_C2H2
 SM00451; ZnF_U1 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS