UniProt Accession

 E5RFR9_HUMAN; E5RFR9 

Genbank Protein ID

 AC022911 

Genbank Nucleotide ID

  

Protein Name

 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform 

Protein Synonyms/Alias

  

Gene Name

 PPP2R2A 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
46	ALCDRHSKLFEEPED	ubiquitination	[1, 2]
166	EASRENNKPRTVLKP	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 197 AA 

Protein Sequence

Gene Ontology

 GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
 GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
 GO:0043278; P:response to morphine; IEA:Compara.
 GO:0007165; P:signal transduction; IEA:InterPro. 

Interpro

 IPR000009; PP2A_PR55.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR017986; WD40_repeat_dom. 

Pfam

  

SMART

  

PROSITE

  

PRINTS

 PR00600; PP2APR55.