CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013596
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leucine-rich repeat-containing protein 57 
Protein Synonyms/Alias
  
Gene Name
 Lrrc57 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
49TIDLSNNKIDSLPPLubiquitination[1]
140LDVVDLSKNQIRSIPubiquitination[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
 REPEAT 39 60 LRR 1.
 REPEAT 63 85 LRR 2.
 REPEAT 86 107 LRR 3.
 REPEAT 109 131 LRR 4.
 REPEAT 132 153 LRR 5.
 REPEAT 154 175 LRR 6.
 REPEAT 177 197 LRR 7.
 REPEAT 202 222 LRR 8.  
Keyword
 Complete proteome; Leucine-rich repeat; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 239 AA 
Protein Sequence
MGNSALRAHV ETAQKTGVFQ LKDRGLTEFP SELQKLTSNL RTIDLSNNKI DSLPPLIIGK 60
FTLLKSLSLN NNKLTVLPDE LCNLKKLETL SLNNNHLREL PSSFGQLSAL KTLSLSGNQL 120
GALPPQLCSL RHLDVVDLSK NQIRSIPDTV GELQAIELNL NQNQISQISV RISCCPRLKV 180
LRLEENCLEL SMLPQSILSD SQICLLAVEG NLFEIKKLRE LEGYDKYMER FTATKKKFA 239 
Gene Ontology
  
Interpro
 IPR001611; Leu-rich_rpt.
 IPR003591; Leu-rich_rpt_typical-subtyp. 
Pfam
 PF00560; LRR_1 
SMART
 SM00369; LRR_TYP 
PROSITE
 PS51450; LRR 
PRINTS