CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025198
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tuftelin-interacting protein 11 
Protein Synonyms/Alias
  
Gene Name
 Tfip11 
Gene Synonyms/Alias
 mCG_3481 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
704AHPSVKDKFNEALDIubiquitination[1]
781FKDLIETKAEEHNIVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix. May also be involved in pre-mRNA splicing (By similarity). 
Sequence Annotation
  
Keyword
 mRNA processing; mRNA splicing; Nucleus; Spliceosome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 838 AA 
Protein Sequence
MSLSHLYRDG EGHLDDDDDD ERENFEITDW DLQNEFNPNR QRHWQTKEEA TYGVWAERDS 60
DEERPSFGGK RARDYSAPVN FISAGLKKGA AEEADSEDSD AEEKPVKQED FPKDLGPKKL 120
KTGGNFKPSQ KGFSGGTKSF MDFGSWERHT KGIGQKLLQK MGYVPGRGLG KNAQGIINPI 180
EAKQRKGKGA VGAYGSERTT QSLQDFPVAD SEEEAEEEFQ KELSQWRKDP SGSKKKPKYS 240
YKTVEELKAK GRVSKKLTAP QKELSQVKVI DMTGREQKVY YSYSQISHKH SVPDEGVPLL 300
AQLPPTAGKE ARMPGFALPE LEHNLQLLIE RTEQEIIQSD RQLQYERDMV VSLSHELEKT 360
AEVLAHEERV ISNLSKVLAL VEECERRMQP HGADPLTLDE CARIFETLQD KYYEEYRLAD 420
RADLAVAIVY PLVKDYFKDW HPLEDGSYGT QIISKWKSLL ENDQLLSHSS QDLSSDAFHR 480
LMWEVWMPFV RNVVAQWQPR NCEPMVDFLD SWAHIIPVWI LDNILDQLIF PKLQKEVDNW 540
NPLTDTVPIH SWIHPWLPLM QARLEPLYSP VRSKLSSALQ KWHPSDASAK LILQPWKEVL 600
TPGSWEAFML RNIVPKLGMC LGELVINPHQ QHMDAFYWVM DWEGMISVSS LVGLLEKHFF 660
PKWLQVLCSW LSNSPNYEEI TKWYLGWKSM FSDQVLAHPS VKDKFNEALD IMNRAVSSNV 720
GAYMQPGARE NIAYLTHTER RKDFQYEAMQ ERREAENMAQ RGIGVAASSV PMNFKDLIET 780
KAEEHNIVFM PVIGKRHEGK QLYTFGRIVI YIDRGVVFVQ GEKTWVPTSL QSLIDMAK 838 
Gene Ontology
 GO:0071013; C:catalytic step 2 spliceosome; IEA:Compara.
 GO:0005737; C:cytoplasm; ISA:MGI.
 GO:0016607; C:nuclear speck; IEA:Compara.
 GO:0005634; C:nucleus; ISA:MGI.
 GO:0005578; C:proteinaceous extracellular matrix; IDA:MGI.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
 GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. 
Interpro
 IPR000467; G_patch_dom.
 IPR022783; GCFC_dom.
 IPR024933; STIP.
 IPR022159; TIP_N. 
Pfam
 PF01585; G-patch
 PF07842; GCFC
 PF12457; TIP_N 
SMART
 SM00443; G_patch 
PROSITE
 PS50174; G_PATCH 
PRINTS