CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013902
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Hippocampus abundant transcript-like protein 1 
Protein Synonyms/Alias
  
Gene Name
 HIATL1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
25EAGAMPEKRAGAQAAubiquitination[1, 2, 3]
246ADPFASLKKVGKDSTubiquitination[1]
247DPFASLKKVGKDSTVubiquitination[2]
460SKASGVQKHSNSSSGubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
 CARBOHYD 463 463 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 506 AA 
Protein Sequence
MSVEPPPELE EKAASEPEAG AMPEKRAGAQ AAGSTWLQGF GRPSVYHAAI VIFLEFFAWG 60
LLTTPMLTVL HETFSQHTFL MNGLIQGVKG LLSFLSAPLI GALSDVWGRK PFLLGTVFFT 120
CFPIPLMRIS PWWYFAMISV SGVFSVTFSV IFAYVADVTQ EHERSTAYGW VSATFAASLV 180
SSPAIGAYLS ASYGDSLVVL VATVVALLDI CFILVAVPES LPEKMRPVSW GAQISWKQAD 240
PFASLKKVGK DSTVLLICIT VFLSYLPEAG QYSSFFLYLR QVIGFGSVKI AAFIAMVGIL 300
SIVAQTAFLS ILMRSLGNKN TVLLGLGFQM LQLAWYGFGS QAWMMWAAGT VAAMSSITFP 360
AISALVSRNA ESDQQGVAQG IITGIRGLCN GLGPALYGFI FYMFHVELTE LGPKLNSNNV 420
PLQGAVIPGP PFLFGACIVL MSFLVALFIP EYSKASGVQK HSNSSSGSLT NTPERGSDED 480
IEPLLQDSSI WELSSFEEPG NQCTEL 506 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:InterPro.
 GO:0005215; F:transporter activity; IEA:InterPro.
 GO:0055085; P:transmembrane transport; IEA:InterPro. 
Interpro
 IPR011701; MFS.
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR005829; Sugar_transporter_CS.
 IPR001958; Tet-R_TetA/multi-R_MdtG. 
Pfam
 PF07690; MFS_1 
SMART
  
PROSITE
 PS50850; MFS
 PS00216; SUGAR_TRANSPORT_1 
PRINTS
 PR01035; TCRTETA.