CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039756
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Tumor necrosis factor receptor superfamily member 1A, membrane form 
Protein Synonyms/Alias
  
Gene Name
 TNFRSF1A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
197MYRYQRWKSKLYSIVubiquitination[1]
199RYQRWKSKLYSIVCGubiquitination[1, 2]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 412 AA 
Protein Sequence
MGLSTVPDLL LPLVLLELLV GIYPSGVIGL VPHLGDREKR DSVCPQGKYI HPQNNSICCT 60
KCHKEMGQVE ISSCTVDRDT VCGCRKNQYR HYWSENLFQC FNCSLCLNGT VHLSCQEKQN 120
TVCTCHAGFF LRENECVSCS NCKKSLECTK LCLPQIENVK GTEDSGTTVL LPLVIFFGLC 180
LLSLLFIGLM YRYQRWKSKL YSIVCGKSTP EKEGELEGTT TKPLAPNPSF SPTPGFTPTL 240
GFSPVPSSTF TSSSTYTPGD CPNFAAPRRE VAPPYQGADP ILATALASDP IPNPLQKWED 300
SAHKPQSLDT DDPATLYAVV ENVPPLRWKE FVRRLGLSDH EIDRLELQNG RCLREAQYSM 360
LATWRRRTPR REATLELLGR VLRDMDLLGC LEDIEEALCG PAALPPAPSL LR 412 
Gene Ontology
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR011029; DEATH-like_dom.
 IPR000488; Death_domain.
 IPR001368; TNFR/NGFR_Cys_rich_reg. 
Pfam
 PF00531; Death
 PF00020; TNFR_c6 
SMART
 SM00005; DEATH
 SM00208; TNFR 
PROSITE
 PS50017; DEATH_DOMAIN
 PS00652; TNFR_NGFR_1
 PS50050; TNFR_NGFR_2 
PRINTS