| Tag | Content |
|---|
| CPLM ID | CPLM-002079 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Amidophosphoribosyltransferase |
Protein Synonyms/Alias | ATase; Glutamine phosphoribosylpyrophosphate amidotransferase |
Gene Name | ADE4 |
Gene Synonyms/Alias | YMR300C; YM9952.02C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 50 | RGRIYQCKGNGMARD | ubiquitination | [1] | | 288 | TRLAMGSKLAENILK | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | |
Sequence Annotation | DOMAIN 2 239 Glutamine amidotransferase type-2.
ACT_SITE 2 2 For GATase activity (By similarity).
METAL 373 373 Magnesium (By similarity).
METAL 374 374 Magnesium (By similarity). |
Keyword | Complete proteome; Glutamine amidotransferase; Glycosyltransferase; Magnesium; Metal-binding; Purine biosynthesis; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 510 AA |
Protein Sequence | MCGILGIVLA NQTTPVAPEL CDGCIFLQHR GQDAAGIATC GSRGRIYQCK GNGMARDVFT 60
QQRVSGLAGS MGIAHLRYPT AGSSANSEAQ PFYVNSPYGI NLAHNGNLVN TASLKRYMDE 120
DVHRHINTDS DSELLLNIFA AELEKHNKYR VNNEDVFHAL EGVYRLCRGG YACVGLLAGF 180
ALFGFRDPNG IRPLLFGERE NPDGTKDYML ASESVVFKAH NFTKYRDLKP GEAVIIPKNC 240
SKGEPEFKQV VPINSYRPDL FEYVYFARPD SVLDGISVYH TRLAMGSKLA ENILKQLKPE 300
DIDVVIPVPD TARTCALECA NVLGKPYREG FVKNRYVGRT FIMPNQRERV SSVRRKLNPM 360
ESEFKGKKVL IVDDSIVRGT TSKEIVNMAK ESGATKVYFA SAAPAIRYNH IYGIDLTDTK 420
NLIAYNRTDE EVAEVIGCER VIYQSLEDLI DCCKTDKITK FEDGVFTGNY VTGVEDGYIQ 480
ELEEKRESIA NNSSDMKAEV DIGLYNCADY 510 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:SGD. GO:0004044; F:amidophosphoribosyltransferase activity; IDA:SGD. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0006189; P:'de novo' IMP biosynthetic process; IMP:SGD. GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW. GO:0009116; P:nucleoside metabolic process; IEA:InterPro. GO:0009113; P:purine nucleobase biosynthetic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |