CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040588
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Nuclear receptor corepressor 2 
Protein Synonyms/Alias
  
Gene Name
 Ncor2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
387SEQENLEKQMRQLAVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2507 AA 
Protein Sequence
MSGSTQPVAQ TWRAAEPRYP PHGISYPVQI ARSHTDVGLL EYQHHPRDYT SHLSPGSIIQ 60
PQRRRPSLLS EFQPGSERSQ ELHLRPESRT FLPELGKPDI EFTESKRPRL ELLPDTLLRP 120
SPLLATGQPS GSEDLTKDRS LAGKLEPVSP PSPPHADPEL ELAPSRLSKE ELIQNMDRVD 180
REITMVEQQI SKLKKKQQQL EEEAAKPPEP EKPVSPPPIE SKHRSLVQII YDENRKKAEA 240
AHRILEGLGP QVELPLYNQP SDTRQYHENI KINQAMRKKL ILYFKRRNHA RKQWEQRFCQ 300
RYDQLMEAWE KKVERIENNP RRRAKESKVR EYYEKQFPEI RKQRELQERM QSRVGQRGSG 360
LSMSAARSEH EVSEIIDGLS EQENLEKQMR QLAVIPPMLY DADQQRIKFI NMNGLMDDPM 420
KVYKDRQVTN MWSEQERDTF REKFMQHPKN FGLIASFLER KTVAECVLYY YLTKKNENYK 480
SLVRRSYRRR GKSQQQQQQQ QQQQQQQMAR SSQEEKEEKE KEKEADKEEE KQDAENEKEE 540
LSKEKTDDTS GEDNDEKEAV ASKGRKTANS QGRRKGRITR SMANEANHEE TATPQQSSEL 600
ASMEMNESSR WTEEEMETAK KGLLEHGRNW SAIARMVGSK TVSQCKNFYF NYKKRQNLDE 660
ILQQHKLKME KERNARRKKK KTPAAASEET AFPPAAEDEE MEASGASANE EELAEEAEAS 720
QASGNEVPRV GECSGPAAVN NSSDTESVPS PRSEATKDTG PKPTGTEALP AATQPPVPPP 780
EEPAVAPAEP SPVPDASGPP SPEPSPSPAA PPATVDKDEQ EAPAAPAPQT EDAKEQKSEA 840
EEIDVGKPEE PEASEEPPES VKSDHKEETE EEPEDKAKGT EAIETVSEAP LKVEEAGSKA 900
AVTKGSSSGA TQDSDSSATC SADEVDEPEG GDKGRLLSPR PSLLTPAGDP RASTSPQKPL 960
DLKQLKQRAA AIPPIVTKVH EPPREDTVPP KPVPPVPPPT QHLQPEGDVS QQSGGSPRGK 1020
SRSPVPPAEK EAEKPAFFPA FPTEGPKLPT EPPRWSSGLP FPIPPREVIK TSPHAADPSA 1080
FSYTPPGHPL PLGLHDSARP VLPRPPISNP PPLISSAKHP GVLERQLGAI SQQGMSVQLR 1140
VPHSEHAKAP MGPLTMGLPL AVDPKKLAPF SGVKQEQLSP RGQAGPPESL GVPTAQETSV 1200
LRGTALGSAT SGSITKGLPS TRAADGPSYR GSITHGTPAD VLYKGTISRI VGEDSPSRLD 1260
RAREDTLPKG HVIYEGKKGH VLSYEGGMSV SQCSKEDGRS SSGPPHETAA PKRTYDMMEG 1320
RVGRTVTSAS IEGLMGRAIP EQHSPHLKEQ HHIRGSITQG IPRSYVEAQE DYLRREAKLL 1380
KREGTPPPPP PPRDLTETYK PRPLDPLGPL KLKPTHEGVV ATVKEAGRSI HEIPREELRR 1440
TPELPLAPRP LKEGSITQGT PLKYDSGAPS TGTKKHDVRS IIGSPGRPFP ALHPLDIMAD 1500
ARALERACYE ESLKSRSGTS SGAGGSITRG APVVVPELGK PRQSPLTYED HGAPFTSHLP 1560
RGSPVTTREP TPRLQEGSLL SSKASQDRKL TSTPREIAKS PHSTVPEHHP HPISPYEHLL 1620
RGVTGVDLYR GHIPLAFDPT SIPRGIPLEA AAAAYYLPRH LAPSPTYPHL YPPYLIRGYP 1680
DTAALENRQT IINDYITSQQ MHHNAASAMA QRADMLRGLS PRESSLALNY AAGPRGIIDL 1740
SQVPHLPVLV PPTPGTPATA IDRLAYLPTA PPPFSSRHSS SPLSPGGPTH LAKPTATSSS 1800
ERERERERER DKSILTSTTT VEHAPIWRPG TEQSSGAGGS SRPASHTHQH SPISPRTQDA 1860
LQQRPSVLHN TSMKGVVTSV EPGTPTVLRW ARSTSTSSPV RPAATFPPAT HCPLGGTLEG 1920
VYPTLMEPVL LPKETSRVAR PERPRVDAGH AFLTKPPARE PASSPSKSSE PRSLAPPSSS 1980
HTAIARTPAK NLAPHHASPD PPAPTSASDL HREKTQSKPF SIQELELRSL GYHSGAGYSP 2040
DGVEPISPVS SPSLTHDKGL SKPLEELEKS HLEGELRHKQ PGPMKLSAEA AHLPHLRPLP 2100
ESQPSSSPLL QTAPGIKGHQ RVVTLAQHIS EVITQDYTRH HPQQLSGPLP APLYSFPGAS 2160
CPVLDLRRPP SDLYLPPPDH GTPARGSPHS EGGKRSPEPS KTSVLGSSED AIEPVSPPEG 2220
MTEPGHARST AYPLLYRDGE QGEPRMGSKS PGNTSQPPAF FSKLTESNSA MVKSKKQEIN 2280
KKLNTHNRNE PEYNIGQPGT EIFNMPAITG AGLMTCRSQA VQEHASTNMG LEAIIRKALM 2340
GKYDQWEEPP PLGANAFNPL NASASLPAAA MPITTADGRS DHALTSPGGG GKAKVSGRPS 2400
SRKAKSPAPG LASGDRPPSV SSVHSEGDCN RRTPLTNRVW EDRPSSAGST PFPYNPLIMR 2460
LQAGVMASPP PPGLAAGSGP LAGPHHAWDE EPKPLLCSQY ETLSDSE 2507 
Gene Ontology
 GO:0000118; C:histone deacetylase complex; IDA:MGI.
 GO:0016604; C:nuclear body; IDA:MGI.
 GO:0003682; F:chromatin binding; IDA:MGI.
 GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
 GO:0003714; F:transcription corepressor activity; IMP:MGI.
 GO:0021846; P:cell proliferation in forebrain; IMP:MGI.
 GO:0042593; P:glucose homeostasis; IMP:MGI.
 GO:0003007; P:heart morphogenesis; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0045599; P:negative regulation of fat cell differentiation; IMP:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0021537; P:telencephalon development; IMP:MGI.
 GO:0050872; P:white fat cell differentiation; IMP:MGI. 
Interpro
 IPR009057; Homeodomain-like.
 IPR001005; SANT/Myb.
 IPR017884; SANT_dom. 
Pfam
 PF00249; Myb_DNA-binding 
SMART
 SM00717; SANT 
PROSITE
 PS51293; SANT 
PRINTS