| Tag | Content |
|---|
| CPLM ID | CPLM-019003 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 566 |
Protein Synonyms/Alias | |
Gene Name | ZNF566 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 235 | FECKECGKTFICGSD | ubiquitination | [1] | | 263 | YECKECGKAFSSGSN | ubiquitination | [1] | | 291 | YECKECGKAFSSGSN | ubiquitination | [1] | | 343 | GEKPYECKECEKAFR | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 6 77 KRAB.
ZN_FING 169 193 C2H2-type 1; degenerate.
ZN_FING 199 221 C2H2-type 2.
ZN_FING 227 249 C2H2-type 3.
ZN_FING 255 277 C2H2-type 4.
ZN_FING 283 395 C2H2-type 5.
ZN_FING 311 333 C2H2-type 6.
ZN_FING 339 361 C2H2-type 7.
ZN_FING 367 389 C2H2-type 8. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 418 AA |
Protein Sequence | MAQESVMFSD VSVDFSQEEW ECLNDDQRDL YRDVMLENYS NLVSMAGHSI SKPNVISYLE 60
QGKEPWLADR ELTRGQWPVL ESRCETKKLF LKKEIYEIES TQWEIMEKLT RRDFQCSSFR 120
DDWECNRQFK KELGSQGGHF NQLVFTHEDL PTLSHHPSFT LQQIINSKKK FCASKEYRKT 180
FRHGSQFATH EIIHTIEKPY ECKECGKSFR HPSRLTHHQK IHTGKKPFEC KECGKTFICG 240
SDLTRHHRIH TGEKPYECKE CGKAFSSGSN FTRHQRIHTG EKPYECKECG KAFSSGSNFT 300
QHQRIHTGEK PYECKECGNA FSQSSQLIKH QRIHTGEKPY ECKECEKAFR SGSDLTRHQR 360
IHTGEKPYEC KICGKAYSQS SQLISHHRIH TSEKPYEYRE CGKNFNYDPQ LIQHQNLYW 419 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |