| Tag | Content |
|---|
| CPLM ID | CPLM-011851 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc-regulated transporter 2 |
Protein Synonyms/Alias | Low-affinity zinc transport protein ZRT2 |
Gene Name | ZRT2 |
Gene Synonyms/Alias | YLR130C; L3120; L9606.9 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 175 | AYSIHNDKTPYTTRN | ubiquitination | [1] | | 191 | EIVATPIKEKEPGSN | ubiquitination | [1] | | 193 | VATPIKEKEPGSNVT | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Low-affinity zinc transport protein. Active in zinc- replete cells and is time-, temperature- and concentration- dependent and prefers zinc over other metals as its substrate. |
Sequence Annotation | REGION 276 277 Heavy metals binding (By similarity).
MOD_RES 148 148 Phosphoserine.
MOD_RES 149 149 Phosphoserine.
MOD_RES 162 162 Phosphoserine.
MOD_RES 170 170 Phosphoserine.
MOD_RES 188 188 Phosphothreonine. |
Keyword | Complete proteome; Ion transport; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport; Zinc; Zinc transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 422 AA |
Protein Sequence | MVDLIARDDS VDTCQASNGY NGHAGLRILA VFIILISSGL GVYFPILSSR YSFIRLPNWC 60
FFIAKFFGSG VIVATAFVHL LQPAAEALGD ECLGGTFAEY PWAFGICLMS LFLLFFTEII 120
THYFVAKTLG HDHGDHGEVT SIDVDAPSSG FVIRNMDSDP VSFNNEAAYS IHNDKTPYTT 180
RNEEIVATPI KEKEPGSNVT NYDLEPGKTE SLANELVPTS SHATNLASVP GKDHYSHEND 240
HQDVSQLATR IEEEDKEQYL NQILAVFILE FGIIFHSVFV GLSLSVAGEE FETLFIVLTF 300
HQMFEGLGLG TRVAETNWPE SKKYMPWLMG LAFTLTSPIA VAVGIGVRHS WIPGSRRALI 360
ANGVFDSISS GILIYTGLVE LMAHEFLYSN QFKGPDGLKK MLSAYLIMCC GAALMALLGK 420
WA 422 |
Gene Ontology | GO:0016021; C:integral to membrane; ISM:SGD. GO:0005886; C:plasma membrane; IMP:SGD. GO:0000007; F:low-affinity zinc ion transmembrane transporter activity; IMP:SGD. GO:0006831; P:low-affinity zinc ion transport; IMP:SGD. |
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Pfam | |
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