CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026024
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dihydrolipoamide acetyltransferase (E2 component of pyruvate dehydrogenase complex) 
Protein Synonyms/Alias
  
Gene Name
 GK1060 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Geobacillus kaustophilus (strain HTA426) 
NCBI Taxa ID
 235909 
Lysine Modification
Position
Peptide
Type
References
95GQEHEEVKKEEKAETacetylation[1]
Reference
 [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus.
 Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG.
 Proteomics. 2013 Aug;13(15):2278-82. [PMID: 23696451] 
Functional Description
  
Sequence Annotation
  
Keyword
 Acyltransferase; Complete proteome; Lipoyl; Pyruvate; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 434 AA 
Protein Sequence
MAFEFKLPDI GEGIHEGEIV KWFVKPGDEV NEDDVLCEVQ NDKAVVEIPS PVKGKVLEIL 60
VPEGTVATVG QTLITLDAPG YENMTFKGQE HEEVKKEEKA ETVSKKEMVE IAAPSAPAAE 120
AEADPNRRVI AMPSVRKYAR EKGVDIRLVQ GTGKNGRILK EDIDAFLAGG AKAAAEPTPQ 180
AAEEKAAPQA PAAKPVVPEG EFPETREKMS GIRRAIAKAM VHSKHTAPHV TLMDEADVTK 240
LVAHRKKFKA IAAEKGIKLT FLPYVVKALV SALREYPVLN TSIDDATEEI IHKHYYNIGI 300
AADTDRGLLV PVIKHADRKP IFALAKEINE LAEKAREGKL MPNEMKGASC TITNIGSAGG 360
QWFTPVINHP EVAILGIGRI AEKPIVRDGE IVAAPVLALS LSFDHRMIDG ATAQKALNHI 420
KQLLSDPELL LMEA 434 
Gene Ontology
 GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:EC. 
Interpro
 IPR003016; 2-oxoA_DH_lipoyl-BS.
 IPR001078; 2-oxoacid_DH_actylTfrase.
 IPR000089; Biotin_lipoyl.
 IPR023213; CAT-like_dom.
 IPR004167; E3-bd.
 IPR011053; Single_hybrid_motif. 
Pfam
 PF00198; 2-oxoacid_dh
 PF00364; Biotin_lipoyl
 PF02817; E3_binding 
SMART
  
PROSITE
 PS50968; BIOTINYL_LIPOYL
 PS00189; LIPOYL 
PRINTS