| Tag | Content |
|---|
| CPLM ID | CPLM-011003 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Medium-chain fatty acid ethyl ester synthase/esterase 1 |
Protein Synonyms/Alias | Alcohol O-acetyltransferase; Ethyl ester biosynthesis protein 1 |
Gene Name | EEB1 |
Gene Synonyms/Alias | YPL095C; LPG13C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 28 | VKHVLGEKGTKSLAF | ubiquitination | [1] | | 128 | EKASFNEKQFSNDEK | ubiquitination | [1] | | 199 | LSKVGDGKFQVVVLN | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by esterification. |
Sequence Annotation | ACT_SITE 251 251 Charge relay system (By similarity).
ACT_SITE 399 399 Charge relay system (By similarity).
ACT_SITE 428 428 Charge relay system (By similarity). |
Keyword | Acyltransferase; Complete proteome; Hydrolase; Reference proteome; Serine esterase; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 456 AA |
Protein Sequence | MFRSGYYPTV TPSHWGYNGT VKHVLGEKGT KSLAFRDSKR QIPLHEFVTK HVPTLKDGAN 60
FRLNSLLFTG YLQTLYLSAG DFSKKFQVFY GREIIKFSDG GVCTADWVMP EWEQTYSLNA 120
EKASFNEKQF SNDEKATHPK GWPRLHPRTR YLSSEELEKC HSKGYSYPLV VVLHGLAGGS 180
HEPLIRALSE DLSKVGDGKF QVVVLNARGC SRSKVTTRRI FTALHTGDVR EFLNHQKALF 240
PQRKIYAVGT SFGAAMLTNY LGEEGDNCPL NAAVALSNPW DFVHTWDKLA HDWWSNHIFS 300
RTLTQFLTRT VKVNMNELQV PENFEVSHKP TVEKPVFYTY TRENLEKAEK FTDILEFDNL 360
FTAPSMGLPD GLTYYRKASS INRLPNIKIP TLIINATDDP VTGENVIPYK QARENPCVLL 420
CETDLGGHLA YLDNESNSWL TKQAAEFLGS FDELVL 456 |
Gene Ontology | GO:0004026; F:alcohol O-acetyltransferase activity; IEA:EC. GO:0034321; F:alcohol O-octanoyltransferase activity; IDA:SGD. GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. GO:0034338; F:short-chain carboxylesterase activity; IDA:SGD. GO:0051792; P:medium-chain fatty acid biosynthetic process; IMP:SGD. GO:0051793; P:medium-chain fatty acid catabolic process; IMP:SGD. |
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PRINTS | |