CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018568
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Synaptopodin-2 
Protein Synonyms/Alias
 Myopodin 
Gene Name
 Synpo2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
25GFRLQGGKEEQQPLQubiquitination[1]
582FPMNRTAKPFLGSMNubiquitination[1]
695MFTFKETKVSPNPELubiquitination[1]
712LLQNAEGKRGTGGDSubiquitination[1]
871KGAQLFAKRQSRMEKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Has an actin-binding and actin-bundling activity. 
Sequence Annotation
 DOMAIN 6 88 PDZ.  
Keyword
 Actin-binding; Alternative splicing; Complete proteome; Cytoplasm; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1087 AA 
Protein Sequence
MGTGDFICIS MTGGAPWGFR LQGGKEEQQP LQVAKIRSQS KASGSGLREG DEVVSINGNP 60
CADLTYPEVI KLMEGITDSL HLLVKRPSSG TSETLDSESE TTNHQHLTHE GPMESTTLQI 120
QQATETQSED FFLAPVQTKV PLTEDQSNAW GYAECPKEEQ APPMLGSQEG HLVEEVILRQ 180
KAEAGQPGHV VELQLSLSKE RHQCTSGPIV TLQGNDKSTS PDPDWSSQLE RTVHINSIPA 240
PEKADTSLTS STSSGRELRV IQGRDPGGAG LPQVEVILDC SDRLKAEECR LQTGRGCVAS 300
PVEGGRSEAP PSLVSFAVSS EGTEHGEDQR SGKDQSRPHK HRARHARLRR SESLSEKQVK 360
EAKSKCKSIA LLLTDAPNPN SKGVLMFKKR RRRARKYTLV SYGTGELERE EEEEEDQEAG 420
DKDEISEVAF LGTSESEVDE ELLSDVDDNT QVVNFDWDSG LVDIEKRLNR GDKMEMLPDT 480
TGKGALMFAK RRERMEQFTA QNEEEKTGGM AGGGPDALQT DGLRTMTSYQ RKEESVRMQS 540
SVSESSFQMG RSLASVPQQN GFSGVSETAG AQRMFPMNRT AKPFLGSMNQ PAAPFSPTRS 600
VTSPISDFPA PPPYSAVSPP PEAFSRGVSS PVAGPAQPPP WPQPAPWSQP AFYDSSEQIA 660
SRDERIAVPA KRTGILQEAK RRGTTKPMFT FKETKVSPNP ELLSLLQNAE GKRGTGGDSG 720
PEEDYLSLGA EACNFMQSSA KQKTPPPVAP KPAVKSPSSS QPVAPVSPVW SPGVAPAQRP 780
AFSTSNPPNP PQVTAVSSIK IAQPAAPPAR PASALNLAGP FKGPQAVVVS HNYTPKPSAP 840
TPLVNAAPAG AGGPSNELPG MSGKGAQLFA KRQSRMEKYV VDSDTVQAHT VRAQSPTPSL 900
PASWKYSSNV RAPPPVAYNP IHSPSYPLAA IKSQPPGAQA SKTSKKKGKK PLNTLDVMKH 960
QPYQLNASLF TFQPPDSKDG LPQKSTVKVS SAPAMKQALP PRQANVGSPT NAQASSVYSV 1020
PAYTSQPNFF AAEATSPVSA SPVPVSVPTS PKQESTSTSY FVAPRPKFSA KKSGVTVQVW 1080
KPSVVEE 1087 
Gene Ontology
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0030018; C:Z disc; ISS:UniProtKB.
 GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.
 GO:0003779; F:actin binding; ISA:MGI.
 GO:0051371; F:muscle alpha-actinin binding; IDA:UniProtKB. 
Interpro
 IPR001478; PDZ. 
Pfam
 PF00595; PDZ 
SMART
 SM00228; PDZ 
PROSITE
 PS50106; PDZ 
PRINTS