CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033776
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leprecan-like 1, isoform CRA_b 
Protein Synonyms/Alias
 Prolyl 3-hydroxylase 2 
Gene Name
 LEPREL1 
Gene Synonyms/Alias
 hCG_1811845 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
143YRVGEYVKALECAKAubiquitination[1]
195TMFVKRHKLESELIKubiquitination[1]
202KLESELIKSAAEGLGubiquitination[1]
324SPHTPNEKFEGATVLubiquitination[1]
332FEGATVLKALKSGYEubiquitination[1]
335ATVLKALKSGYEGRVubiquitination[1]
414PEANECWKEPPAYTFubiquitination[1]
474GENPHGVKAVTKGKRubiquitination[1]
516LDQEQQGKHELNINPubiquitination[1]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 527 AA 
Protein Sequence
MEMQQNIENY RATAGVEALQ LVDREAKPHM ESYNAGVKHY EADDFEMAIR HFEQALREYF 60
VEDTECRTLC EGPQRFEEYE YLGYKAGLYE AIADHYMQVL VCQHECVREL ATRPGRLSPI 120
ENFLPLHYDY LQFAYYRVGE YVKALECAKA YLLCHPDDED VLDNVDYYES LLDDSIDPAS 180
IEAREDLTMF VKRHKLESEL IKSAAEGLGF SYTEPNYWIR YGGRQDENRV PSGVNVEGAE 240
VHGFSMGKKL SPKIDRDLRE GGPLLYENIT FVYNSEQLNG TQRVLLDNVL SEEQCRELHS 300
VASGIMLVGD GYRGKTSPHT PNEKFEGATV LKALKSGYEG RVPLKSARLF YDISEKARRI 360
VESYFMLNST LYFSYTHMVC RTALSGQQDR RNDLSHPIHA DNCLLDPEAN ECWKEPPAYT 420
FRDYSALLYM NDDFEGGEFI FTEMDAKTVT ASIKPKCGRM ISFSSGGENP HGVKAVTKGK 480
RCAVALWFTL DPLYRELERI QADEVIAILD QEQQGKHELN INPKDEL 527 
Gene Ontology
 GO:0005604; C:basement membrane; IEA:Compara.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0031418; F:L-ascorbic acid binding; IEA:InterPro.
 GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro. 
Interpro
 IPR005123; Oxoglu/Fe-dep_dioxygenase.
 IPR006620; Pro_4_hyd_alph.
 IPR011990; TPR-like_helical. 
Pfam
 PF13640; 2OG-FeII_Oxy_3 
SMART
 SM00702; P4Hc 
PROSITE
 PS51471; FE2OG_OXY 
PRINTS