UniProt Accession

 K7EJH8_HUMAN; K7EJH8 

Genbank Protein ID

 AC008649; AC022144 

Genbank Nucleotide ID

  

Protein Name

 Alpha-actinin-4 

Protein Synonyms/Alias

  

Gene Name

 ACTN4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
18	IEYDKLRKDDPVTNL	ubiquitination	[1]
34	NAFEVAEKYLDIPKM	ubiquitination	[2]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 182 AA 

Protein Sequence

Gene Ontology

 GO:0051764; P:actin crosslink formation; IEA:InterPro.
 GO:0051017; P:actin filament bundle assembly; IEA:InterPro. 

Interpro

 IPR026921; Alpha-actinin.
 IPR001715; CH-domain.
 IPR002017; Spectrin_repeat. 

Pfam

 PF00307; CH
 PF00435; Spectrin 

SMART

  

PROSITE

  

PRINTS