UniProt Accession

 H0YJ92_HUMAN; H0YJ92 

Genbank Protein ID

 AL132777; AL160236 

Genbank Nucleotide ID

  

Protein Name

 CDK-activating kinase assembly factor MAT1 

Protein Synonyms/Alias

  

Gene Name

 MNAT1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
27	QRRLFIQKEEQLQQI	ubiquitination	[1, 2, 3]
40	QILKRKNKQAFLDEL	ubiquitination	[2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 169 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0007512; P:adult heart development; IEA:Compara.
 GO:0006915; P:apoptotic process; IEA:Compara.
 GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Compara.
 GO:0044236; P:multicellular organismal metabolic process; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Compara.
 GO:0050790; P:regulation of catalytic activity; IEA:Compara.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0051592; P:response to calcium ion; IEA:Compara.
 GO:0021591; P:ventricular system development; IEA:Compara. 

Interpro

 IPR015877; Cdk-activating_kinase_MAT1_cen.
 IPR004575; MAT1/Tfb3.
 IPR003903; Ubiquitin-int_motif. 

Pfam

 PF06391; MAT1 

SMART

  

PROSITE

 PS50330; UIM 

PRINTS