UniProt Accession

 D3YZZ6_MOUSE; D3YZZ6 

Genbank Protein ID

 AC119873; AC121794 

Genbank Nucleotide ID

  

Protein Name

 Eukaryotic translation initiation factor 2A 

Protein Synonyms/Alias

  

Gene Name

 Eif2a 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
23	RESGRNCKVYTFSKD	ubiquitination	[1]
152	ANKLHLQKVNDFNLS	ubiquitination	[1]
175	AVYVPGSKGAPSFVR	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 251 AA 

Protein Sequence

Gene Ontology

 GO:0005850; C:eukaryotic translation initiation factor 2 complex; IEA:Compara.
 GO:0043022; F:ribosome binding; IEA:Compara.
 GO:0003743; F:translation initiation factor activity; IEA:Compara.
 GO:0000049; F:tRNA binding; IEA:Compara.
 GO:0009967; P:positive regulation of signal transduction; IDA:MGI.
 GO:0006468; P:protein phosphorylation; IDA:MGI.
 GO:0006417; P:regulation of translation; IEA:Compara.
 GO:0042255; P:ribosome assembly; IEA:Compara.
 GO:0032933; P:SREBP signaling pathway; IDA:MGI.
 GO:0006413; P:translational initiation; IEA:GOC. 

Interpro

 IPR013979; TIF_beta_prop-like.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR017986; WD40_repeat_dom. 

Pfam

 PF08662; eIF2A 

SMART

  

PROSITE

  

PRINTS