CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016736
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Septin-10 
Protein Synonyms/Alias
  
Gene Name
 Sept10 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
8MASCDEIKEHPRSLSacetylation[1]
173TMKSLDNKVNIIPLIubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). 
Sequence Annotation
 NP_BIND 46 53 GTP (By similarity).
 NP_BIND 182 190 GTP (By similarity).
 BINDING 101 101 GTP; via amide nitrogen (By similarity).
 BINDING 236 236 GTP; via amide nitrogen and carbonyl
 BINDING 251 251 GTP (By similarity).  
Keyword
 Alternative splicing; Cell cycle; Cell division; Complete proteome; Cytoplasm; Cytoskeleton; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 452 AA 
Protein Sequence
MASCDEIKEH PRSLSMCGHV GFESLPDQLV DRSIEQGFCF NILCVGETGI GKSTLINTLF 60
NTNFEELESS HFCPCVRLRA QTYELQESNV RLKLTIVNTV GFGDQINKED SYQPIVDYID 120
DQFEAYLQEE VKIKRALFNY HDSRIHVCLY FIAPTGHSLR TLDLLTMKSL DNKVNIIPLI 180
AKADTISKSE LQKFKMKLMN ELVINGVQIY QFPTDDDTTS KINGAMNGHL PFAVVGSMDE 240
IKVGNKMVKG RQYPWGIVQV ENENHCDFVK LREMLICTNM EDLREQTHMR HYELYRRCKL 300
QEMGFVDMGP ENKPLSLQET YEAKRHEFYG ERQRKEEQMK QMFVQRVKEK EAILKEAERE 360
LQAKFEHLKR IHQEERMKLE EKRRMLEEES VAFAKKKATC ELFPNQSFLA SGSSIRKDKD 420
RKKADGASAF CDCLTAQESV RLCISSPRKD MD 452 
Gene Ontology
 GO:0031105; C:septin complex; IEA:InterPro.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW. 
Interpro
 IPR000038; Cell_div_GTP-bd.
 IPR027417; P-loop_NTPase.
 IPR016491; Septin. 
Pfam
 PF00735; Septin 
SMART
  
PROSITE
  
PRINTS