UniProt Accession

 VP37D_HUMAN; Q86XT2; Q6P2C3 

Genbank Protein ID

 AY081952; AC073846; BC064621 

Genbank Nucleotide ID

 AAL91075.1; AAH64621.2 

Protein Name

 Vacuolar protein sorting-associated protein 37D 

Protein Synonyms/Alias

 ESCRT-I complex subunit VPS37D; Williams-Beuren syndrome chromosomal region 24 protein 

Gene Name

 VPS37D 

Gene Synonyms/Alias

 WBSCR24 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
99	VAENCADKLQRLEES	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. 

Sequence Annotation

 DOMAIN 93 182 VPS37 C-terminal.  

Keyword

 Complete proteome; Endosome; Membrane; Protein transport; Reference proteome; Transport; Williams-Beuren syndrome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 251 AA 

Protein Sequence

Gene Ontology

 GO:0000813; C:ESCRT I complex; IDA:UniProtKB.
 GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
 GO:0016044; P:cellular membrane organization; TAS:Reactome.
 GO:0046788; P:egress of virus within host cell; TAS:Reactome.
 GO:0016197; P:endosomal transport; TAS:Reactome.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0019082; P:viral protein processing; TAS:Reactome.
 GO:0019068; P:virion assembly; TAS:Reactome. 

Interpro

 IPR009851; Mod_r. 

Pfam

 PF07200; Mod_r 

SMART

  

PROSITE

 PS51314; VPS37_C 

PRINTS