CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015221
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 TLD domain-containing protein 1 
Protein Synonyms/Alias
 TBC/LysM-associated domain-containing protein 1 
Gene Name
 TLDC1 
Gene Synonyms/Alias
 KIAA1609 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
122SATEGPVKAREVQKFubiquitination[1]
153ELRGWTGKEAPGPNPubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 DOMAIN 268 412 TLD.
 LIPID 2 2 N-myristoyl glycine.  
Keyword
 Complete proteome; Lipoprotein; Myristate; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 456 AA 
Protein Sequence
MGNSRSRVGR SFCSQFLPEE QAEIDQLFDA LSSDKNSPNV SSKSFSLKAL QNHVGEALPP 60
EMVTRLYDGM RRVDLTGKAK GPSENVSQEQ FTASMSHLLK GNSEEKSLMI MKMISATEGP 120
VKAREVQKFT EDLVGSVVHV LSHRQELRGW TGKEAPGPNP RVQVLAAQLL SDMKLQDGKR 180
LLGPQWLDYD CDRAVIEDWV FRVPHVAIFL SVVICKGFLI LCSSLDLTTL VPERQVDQGR 240
GFESILDVLS VMYINAQLPR EQRHRWCLLF SSELHGHSFS QLCGHITHRG PCVAVLEDHD 300
KHVFGGFASC SWEVKPQFQG DNRCFLFSIC PSMAVYTHTG YNDHYMYLNH GQQTIPNGLG 360
MGGQHNYFGL WVDVDFGKGH SRAKPTCTTY NSPQLSAQEN FQFDKMEVWA VGDPSEEQLA 420
KGNKSILDAD PEAQALLEIS GHSRHSEGLR EVPDDE 456 
Gene Ontology
  
Interpro
 IPR006571; TLDc. 
Pfam
 PF07534; TLD 
SMART
 SM00584; TLDc 
PROSITE
  
PRINTS