CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012759
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative deoxyribonuclease TATDN3 
Protein Synonyms/Alias
  
Gene Name
 TATDN3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
86DQRSVTLKDLDVALPubiquitination[1]
99LPIIENYKDRLLAIGubiquitination[1]
123FAGTGEQKEEQRQVLubiquitination[1]
226SPALGPEKQVRNEPWubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Putative deoxyribonuclease. 
Sequence Annotation
 METAL 12 12 Divalent metal cation 1.
 METAL 14 14 Divalent metal cation 1.
 METAL 107 107 Divalent metal cation 1.
 METAL 107 107 Divalent metal cation 2.
 METAL 147 147 Divalent metal cation 2.
 METAL 170 170 Divalent metal cation 2.
 METAL 218 218 Divalent metal cation 1.  
Keyword
 3D-structure; Alternative splicing; Complete proteome; Hydrolase; Metal-binding; Nuclease; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 274 AA 
Protein Sequence
MRAAGVGLVD CHCHLSAPDF DRDLDDVLEK AKKANVVALV AVAEHSGEFE KIMQLSERYN 60
GFVLPCLGVH PVQGLPPEDQ RSVTLKDLDV ALPIIENYKD RLLAIGEVGL DFSPRFAGTG 120
EQKEEQRQVL IRQIQLAKRL NLPVNVHSRS AGRPTINLLQ EQGAEKVLLH AFDGRPSVAM 180
EGVRAGYFFS IPPSIIRSGQ KQKLVKQLPL TSICLETDSP ALGPEKQVRN EPWNISISAE 240
YIAQVKGISV EEVIEVTTQN ALKLFPKLRH LLQK 274 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 
Interpro
 IPR001130; TatD_family. 
Pfam
 PF01026; TatD_DNase 
SMART
  
PROSITE
 PS01090; TATD_2
 PS01091; TATD_3 
PRINTS