CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025193
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Adcy4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
549IEQLNSQKQWKQSKDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Lyase; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1077 AA 
Protein Sequence
MARLFSPRPP PSEDLFYETY YSLSQQYPLL ILLLVIVLCA LVALPAVAWA SGRELTSDPS 60
FLTTVLCALG GFSLLLGLAS REQQLQRWTR PLSGLIWVAL LALGYGFLFT GGVVSAWDQV 120
SFFLFIIFTV YAMLPLGMRD AAAAGVISSL SHLLVLGLYL GWQPESQRAL LPQLAANAVL 180
FLCGNVVGAY HKALMERALR ATFREALSSL HSRRRLDTEK KHQEHLLLSI LPAYLAREMK 240
AEIMARLQAG QRSRPENTNN FHSLYVKRHQ GVSVLYADIV GFTRLASECS PKELVLMLNE 300
LFGKFDQIAK EHECMRIKIL GDCYYCVSGL PLSLPDHAIN CVRMGLDMCR AIRKLRVATG 360
VDINMRVGVH SGSVLCGVIG LQKWQYDVWS HDVTLANHME AGGVPGRVHI TGATLALLAG 420
AYAVERADTE HRDPYLRELG EPTYLVIDPR AEEEDEKGTA KGLLSSLEGH TMRPSLLMTR 480
YLESWGAAKP FAHLSHLDSP VSTSTPLPEK AFSPQWSLDR SRTPRGLDDE LGTGDAKFFQ 540
VIEQLNSQKQ WKQSKDFNLL TLYFREKEME KQYRLSALPA FKYYAACTFL VFLSNFTIQM 600
LVTTRPPALI ITYSITFLLF FLLLFVCFSE HLTKCVQKGP KMLHWLPALS VLVATRPGFR 660
VALGTATILL VFTMAIASLL FLPVSSDCLF LASNVSSVTF NASWEMPGSL PLISIPLISI 720
PYSMHCCVLG FLSCSLFLHM SFELKLLLLL LWLVASCSLF LHSHAWLSDC LIARLYQSPS 780
DSRPGVLKEP KLMGAIYFFI FFFTLLVLAR QNEYYCRLDF LWKKKLRQER EETETMENLT 840
RLLLENVLPA HVAPQFIGQN RRNEDLYHQS YECVCVLFAS VPDFKEFYSE SNINHEGLEC 900
LRLLNEIIAD FDELLSKPKF SGVEKIKTIG STYMAATGLN ATSGQDTQQD SERSCSHLGT 960
MVEFAVALGS KLGVINKHSF NNFRLRVGLN HRPVVAGVIG AQKPQYDIWG NTVNVASRME 1020
STGVLGKIQV TEETARALQS LGYTCYSRGS IKVKGKGELC TYFLNTDLTR TGSPSAS 1077 
Gene Ontology
 GO:0030425; C:dendrite; IDA:MGI.
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005622; C:intracellular; IDA:MGI.
 GO:0005886; C:plasma membrane; TAS:MGI.
 GO:0004016; F:adenylate cyclase activity; TAS:MGI.
 GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
 GO:0007190; P:activation of adenylate cyclase activity; TAS:MGI.
 GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IDA:MGI.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro. 
Interpro
 IPR001054; A/G_cyclase.
 IPR018297; A/G_cyclase_CS.
 IPR009398; Adenylate_cyclase-like. 
Pfam
 PF06327; DUF1053
 PF00211; Guanylate_cyc 
SMART
 SM00044; CYCc 
PROSITE
 PS00452; GUANYLATE_CYCLASE_1
 PS50125; GUANYLATE_CYCLASE_2 
PRINTS