UniProt Accession

 TALB_ECOLI; P0A870; P30148 

Genbank Protein ID

 D13161; S80045; U00096; AP009048 

Genbank Nucleotide ID

 BAA21822.1; AAB47022.1; AAC73119.1; BAB96586.1 

Protein Name

 Transaldolase B 

Protein Synonyms/Alias

  

Gene Name

 talB 

Gene Synonyms/Alias

 yaaK; b0008; JW0007 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
4	****MTDKLTSLRQY	acetylation	[1]
25	TGDIAAMKLYQPQDA	acetylation	[1]
50	AQIPEYRKLIDDAVA	acetylation	[1, 2]
60	DDAVAWAKQQSNDRA	acetylation	[1]
117	AKAKRLIKLYNDAGI	acetylation	[1, 2]
132	SNDRILIKLASTWQG	acetylation	[1]
148	RAAEQLEKEGINCNL	acetylation	[1]
187	GRILDWYKANTDKKE	acetylation	[1, 3]
192	WYKANTDKKEYAPAE	acetylation	[1]
193	YKANTDKKEYAPAED	acetylation	[1]
250	TIAPALLKELAESEG	acetylation	[1, 2, 3]
270	LSYTGEVKARPARIT	acetylation	[1]
294	QDPMAVDKLAEGIRK	acetylation	[1]
301	KLAEGIRKFAIDQEK	acetylation	[1, 2]
308	KFAIDQEKLEKMIGD	acetylation	[1, 2, 3]
311	IDQEKLEKMIGDLL*	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111]
 [3] The diversity of lysine-acetylated proteins in Escherichia coli.
 Yu BJ, Kim JA, Moon JH, Ryu SE, Pan JG.
 J Microbiol Biotechnol. 2008 Sep;18(9):1529-36. [PMID: 18852508] 

Functional Description

 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. 

Sequence Annotation

 ACT_SITE 132 132 Schiff-base intermediate with substrate.  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Pentose shunt; Reference proteome; Schiff base; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 317 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0016020; C:membrane; IDA:UniProtKB.
 GO:0004801; F:sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity; IEA:HAMAP.
 GO:0006098; P:pentose-phosphate shunt; IEA:HAMAP. 

Interpro

 IPR013785; Aldolase_TIM.
 IPR001585; Transaldolase.
 IPR004730; Transaldolase_1.
 IPR018225; Transaldolase_AS. 

Pfam

 PF00923; Transaldolase 

SMART

  

PROSITE

 PS01054; TRANSALDOLASE_1
 PS00958; TRANSALDOLASE_2 

PRINTS