| Tag | Content |
|---|
| CPLM ID | CPLM-008020 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ATP-binding cassette sub-family D member 1 |
Protein Synonyms/Alias | Adrenoleukodystrophy protein; ALDP |
Gene Name | Abcd1 |
Gene Synonyms/Alias | Ald; Aldgh |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 602 | WEAVCDWKDVLSGGE | ubiquitination | [1] | | 610 | DVLSGGEKQRIGMAR | ubiquitination | [1] | | 696 | RLSLTEEKQRLEQQL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Probable transporter. Could be involved in the import of VLCFA-CoA synthetase into the peroxisomal membrane. |
Sequence Annotation | DOMAIN 94 386 ABC transmembrane type-1.
DOMAIN 474 729 ABC transporter.
NP_BIND 507 514 ATP (By similarity).
REGION 67 186 Interaction with PEX19 (By similarity).
CARBOHYD 214 214 N-linked (GlcNAc...) (Potential). |
Keyword | ATP-binding; Complete proteome; Glycoprotein; Membrane; Nucleotide-binding; Peroxisome; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 736 AA |
Protein Sequence | MPVLSTPRPS RVTTLKRTAV VLALTAYGVH KIYPLVRQCL TPARGPQVPA GEPTQEASGA 60
TATKAGMNRV FLQRLLALLR LLFPRVLCRE TGLLALHSAA LVSRTFLSVY VARLDGRLAR 120
CIVRKDPRAF SWQLLQWLLI ALPATFINSA IRYLEGQLAL SFRSRLVAHA YGLYFSQQTY 180
YRVSNMDGRL RNPDQSLTED VVAFAASVAH LYSNLTKPLL DVAVTSYTLL RAARSRGAGT 240
AWPSAIAGLV VFLTANVLRA FSPKFGELVA EEARRKGELR YMHSRVVANS EEIAFYGGHE 300
VELALLQHSY QDLASQINLI LLERLWYVML EQFLMKYVWS ASGLLMVAVP IITATGYAES 360
DSEAMKKAAL EMKEEELVSE RTEAFTIARN LLTAAADATE RIMSSYKEVT ELAGYTARVY 420
EMFQVFEDVK HCRFKRTGDL EEAQAGPGVM VQSGVHVEGP LKIQGQVVDV EQGIICENIP 480
IITPTGEVVV ASLNIRVEEG MHLLITGPNG CGKSSLFRIL GGLWPTYSGV LYKPPPQRMF 540
YIPQRPYMSV GSLRDQVIYP DSAEDMRRKG CSEQQLEAIL GIVHLRHILQ REGGWEAVCD 600
WKDVLSGGEK QRIGMARMFY HRPKYALLDE CTSAVSIDVE GKIFQAAKDA GIALLSITHR 660
PSLWKYHTHL LQFDGEGGWK FEKLDSAARL SLTEEKQRLE QQLAGIPKMQ GRLQELRQIL 720
GEAAAPVQPL VPGVPT 736 |
Gene Ontology | GO:0005779; C:integral to peroxisomal membrane; IEA:Compara. GO:0005739; C:mitochondrion; IDA:MGI. GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara. GO:0005778; C:peroxisomal membrane; IDA:HGNC. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0016887; F:ATPase activity; IEA:Compara. GO:0005325; F:peroxisomal fatty-acyl-CoA transporter activity; IEA:Compara. GO:0006635; P:fatty acid beta-oxidation; IMP:UniProtKB. GO:0042758; P:long-chain fatty acid catabolic process; IEA:Compara. GO:0042760; P:very long-chain fatty acid catabolic process; IEA:Compara. |
Interpro | |
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PROSITE | |
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