CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037089
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 
Protein Synonyms/Alias
  
Gene Name
 PLOD2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
286NKEVYHEKDIKVFFDubiquitination[1]
289VYHEKDIKVFFDKAKubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 703 AA 
Protein Sequence
MQSAKYFNYT VKVLGQGEEW RGGDGINSIG GGQKVRLMKE VMEHYADQDD LVVMFTECFD 60
VIFAGGPEEV LKKFQKANHK VVFAADGILW PDKRLADKYP VVHIGKRYLN SGGFIGYAPY 120
VNRIVQQWNL QDNDDDQLFY TKVYIDPLKR EAINITLDHK CKIFQTLNGA VDEVVLKFEN 180
GKARAKNTFY ETLPVAINGN GPTKILLNYF GNYVPNSWTQ DNGCTLCEFD TVDLSAVDVH 240
PNVSIGVFIE QPTPFLPRFL DILLTLDYPK EALKLFIHNK EVYHEKDIKV FFDKAKHEIK 300
TIKIVGPEEN LSQAEARNMG MDFCRQDEKC DYYFSVDADV VLTNPRTLKI LIEQNRKIIA 360
PLVTRHGKLW SNFWGALSPD GYYARSEDYV DIVQGNRVGV WNVPYMANVY LIKGKTLRSE 420
MNERNYFVRD KLDPDMALCR NAREMTLQRE KDSPTPETFQ MLSPPKGVFM YISNRHEFGR 480
LLSTANYNTS HYNNDLWQIF ENPVDWKEKY INRDYSKIFT ENIVEQPCPD VFWFPIFSEK 540
ACDELVEEME HYGKWSGGKH HDSRISGGYE NVPTDDIHMK QVDLENVWLH FIREFIAPVT 600
LKVFAGYYTK GFALLNFVVK YSPERQRSLR PHHDASTFTI NIALNNVGED FQGGGCKFLR 660
YNCSIESPRK GWSFMHPGRL THLHEGLPVK NGTRYIAVSF IDP 703 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0031418; F:L-ascorbic acid binding; IEA:InterPro.
 GO:0008475; F:procollagen-lysine 5-dioxygenase activity; IEA:InterPro. 
Interpro
 IPR005123; Oxoglu/Fe-dep_dioxygenase.
 IPR006620; Pro_4_hyd_alph.
 IPR001006; Procol_lys_dOase. 
Pfam
 PF03171; 2OG-FeII_Oxy 
SMART
 SM00702; P4Hc 
PROSITE
 PS51471; FE2OG_OXY
 PS01325; LYS_HYDROXYLASE 
PRINTS