CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038996
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Dhtkd1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
154ARRFEELKKETFTTEacetylation[1]
168EERKHLSKLLLESQEacetylation[1]
183FDHFLATKFATVKRYacetylation[1]
188ATKFATVKRYGGEGAacetylation[1]
487IKASYYAKLNGHLANacetylation[1]
795MAPGTAFKPVIGDSSacetylation[1]
806GDSSVDPKNVKTLIFacetylation[1]
824KHFYALLKQRESLGAacetylation[1]
833RESLGAKKRDFAIIRacetylation[1]
922QHEAILFKTFTS***acetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 926 AA 
Protein Sequence
MASATVAAAG RALRRAVPLL RRSYQTERGV YGYRPRKAGS GEPRGDRARP SVDHGLARLV 60
TVYCEHGHKA AQINPLFPGQ ALLDTVPEIQ ALVQTLQGPF TTTGLLNMGK EEASLEEVLA 120
YLNHIYCGPI SIETAQLQSQ EEKDWFARRF EELKKETFTT EERKHLSKLL LESQEFDHFL 180
ATKFATVKRY GGEGAESMMG FFHELLKLSA YGGITDIIIG MPHRGRLNLL TGLLQLPPEL 240
MFRKMRGLSE FPENVAAIGD VLSHLTSSVD LDFGAHRPLH VTMLPNPSHL EAINPVAVGK 300
TRGRQQSQED GDYSPNGSAQ PGDKVICLQV HGDASFCGQG IVLETFTLSN LPHFRIGGSI 360
HLIVNNQLGY TTPAERGRSS LYSSDIGKLV GCAIIHVNGD SPEEVVRATR LAFEYQRQFR 420
KDVIIDLLCY RQWGHNELDE PFFTNPVMYK IIRARKSIPD TYAEHLIASG LMTQEEVSDI 480
KASYYAKLNG HLANVAHYSP PAPHLQARWQ GLVQPAACVT TWDTGVPLEL LRFVGVKSVE 540
VPEELQLHSH LLKMYVQQSR MEKVKNGTNL DWATAETLAL GSLLAQGFNV RLSGQDVGRG 600
TFSQRHAMVV CQNTDDVYIP LNHMDPNQKG FLESCVSNNY LSEQLMIFME TDYSFKVNLV 660
VHRLLSNCRF WFENITCVFV TLLXEGHGRA GLLFCSHFFF NMNHAFDFSF PVLSCCTIER 720
NIFTKMCDSA EEGVDSDTVN MFVVHPTTPA QYFHLLRRQM MRNFRKPLIA SPKMLLRYPV 780
AVSTLEEMAP GTAFKPVIGD SSVDPKNVKT LIFCSGKHFY ALLKQRESLG AKKRDFAIIR 840
LEELCPFPLD SLQQEMGKYK HVQDIIWSQE EPQNMGPWSF VYPRFEKQLA CKLRLVSRPP 900
LPAPAVGIGT VHQQQHEAIL FKTFTS 926 
Gene Ontology
 GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.
 GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
 GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro. 
Interpro
 IPR011603; 2oxoglutarate_DH_E1.
 IPR001017; DH_E1.
 IPR005475; Transketolase-like_Pyr-bd. 
Pfam
 PF00676; E1_dh
 PF02779; Transket_pyr 
SMART
  
PROSITE
  
PRINTS