| Tag | Content |
|---|
| CPLM ID | CPLM-010923 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Guanylate cyclase soluble subunit beta-1 |
Protein Synonyms/Alias | GCS-beta-1; Guanylate cyclase soluble subunit beta-3; GCS-beta-3; Soluble guanylate cyclase small subunit |
Gene Name | GUCY1B3 |
Gene Synonyms/Alias | GUC1B3; GUCSB3; GUCY1B1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 26 | PEVWEDIKKEAQLDE | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | |
Sequence Annotation | DOMAIN 421 554 Guanylate cyclase.
METAL 105 105 Iron (heme proximal ligand) (By |
Keyword | 3D-structure; Alternative splicing; cGMP biosynthesis; Complete proteome; Cytoplasm; Direct protein sequencing; GTP-binding; Heme; Iron; Lyase; Metal-binding; Nucleotide-binding; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 619 AA |
Protein Sequence | MYGFVNHALE LLVIRNYGPE VWEDIKKEAQ LDEEGQFLVR IIYDDSKTYD LVAAASKVLN 60
LNAGEILQMF GKMFFVFCQE SGYDTILRVL GSNVREFLQN LDALHDHLAT IYPGMRAPSF 120
RCTDAEKGKG LILHYYSERE GLQDIVIGII KTVAQQIHGT EIDMKVIQQR NEECDHTQFL 180
IEEKESKEED FYEDLDRFEE NGTQESRISP YTFCKAFPFH IIFDRDLVVT QCGNAIYRVL 240
PQLQPGNCSL LSVFSLVRPH IDISFHGILS HINTVFVLRS KEGLLDVEKL ECEDELTGTE 300
ISCLRLKGQM IYLPEADSIL FLCSPSVMNL DDLTRRGLYL SDIPLHDATR DLVLLGEQFR 360
EEYKLTQELE ILTDRLQLTL RALEDEKKKT DTLLYSVLPP SVANELRHKR PVPAKRYDNV 420
TILFSGIVGF NAFCSKHASG EGAMKIVNLL NDLYTRFDTL TDSRKNPFVY KVETVGDKYM 480
TVSGLPEPCI HHARSICHLA LDMMEIAGQV QVDGESVQIT IGIHTGEVVT GVIGQRMPRY 540
CLFGNTVNLT SRTETTGEKG KINVSEYTYR CLMSPENSDP QFHLEHRGPV SMKGKKEPMQ 600
VWFLSRKNTG TEETKQDDD 619 |
Gene Ontology | GO:0008074; C:guanylate cyclase complex, soluble; TAS:ProtInc. GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0004383; F:guanylate cyclase activity; TAS:ProtInc. GO:0020037; F:heme binding; IEA:Compara. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0004872; F:receptor activity; TAS:ProtInc. GO:0008015; P:blood circulation; TAS:ProtInc. GO:0007596; P:blood coagulation; TAS:Reactome. GO:0007263; P:nitric oxide mediated signal transduction; TAS:ProtInc. |
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PROSITE | |
PRINTS | |