CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018181
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MIT domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 Mitd1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
3*****MAKSSLGQDSacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
 Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex (By similarity). 
Sequence Annotation
 DOMAIN 8 86 MIT.
 REGION 168 231 Important for association with membranes  
Keyword
 3D-structure; Cell cycle; Cell division; Complete proteome; Endosome; Membrane; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 249 AA 
Protein Sequence
MAKSSLGQDS DSTAAVAVLK RAVELDAESR YQQALVCYQE GIDMLLQVLK GTKESSKRCV 60
LRTKISGYMD RAENIKKYLD QEKEDGKYHK QIKIEENATG FSYESLFREY LHETVTEVWI 120
EDPYIRQTHQ LYNFLRFCEM LIKKPCKVRT IHLLTSGYEG LGNTQQSSGL EEIKQSLGSH 180
GVVLEINYSS SIHDREIRFN NGWMIKIGRG LDYFKKPQGR FSLGYYDLDL RPCHETTVDI 240
FHNKHTKKI 249 
Gene Ontology
 GO:0019898; C:extrinsic to membrane; IEA:Compara.
 GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
 GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
 GO:0000281; P:mitotic cytokinesis; IEA:Compara.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 
Interpro
 IPR007330; MIT. 
Pfam
 PF04212; MIT 
SMART
 SM00745; MIT 
PROSITE
  
PRINTS